The Role of Artificial Intelligence for Image Analysis in Surgical Pathology

Bălțătescu, Gabriela Izabela; Aşchie, Mariana; Deacu, Mariana; Petcu, Lucian Cristian; Dobrin, Nicolae; Nicolau, Anca Antonela; Chisoi, Anca; Burlacu, Ionuţ; Iordache, Ionut Eduard; Liliana, Steriu

doi:10.35219/eai15840409104

Cited by 3 publications

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“…The slides were evaluated by a Nikon Eclipse E600 microscope and representative photos were taken from digital whole slide images, obtained with a HuronTISSUEScope TM 4000XT scanner [ 20 ].…”

Section: Case Presentationmentioning

confidence: 99%

Concurrent Tumors Revealed by an Autopsy-A Case Report and Literature Review

Cristian

Boşoteanu

Aşchie

et al. 2022

Case Reports in Gastrointestinal Medicine

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Introduction. Multiple primary malignant neoplasms are an uncommon phenomenon, given the very low incidence of two or more different tumors, while neoplasm may be limited to a single organ or may involve multiple separate anatomical organs. The main purpose of this study is to highlight the importance of morphological and immunohistochemical tests to distinguish the origin of the primary tumor. Case Presentation. We report the case of a 65-year-old deceased male, presenting multiple tumors in the lung, stomach, kidneys, and adrenal organs. The main symptoms presented by the patient were dyspnea with a range of 77% with oxygen saturation, fatigability, and productive cough. Histopathological examination revealed a solid and papillary lung adenocarcinoma, concurrent with tubular gastric adenocarcinoma. Immunohistochemical testing was mandatory by using a panel of seven monoclonal mouse antibodies (TTF-1, Napsin A, CK7, CK20, p40, synaptophysin, and chromogranin A). The pulmonary tumoral immunophenotype (positive for TTF-1, Napsin A, CK7; negative for CK20, p40, synaptophysin, and chromogranin A) confirms the diagnosis of primary lung ADC and invalidates the hypothesis of a metastasis arisen from a gastric adenocarcinoma or other forms of lung cancer. Conclusion. The importance of the ancillary test is to distinguish a primary tumor from a metastatic one.

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Section: Case Presentationmentioning

confidence: 99%

Concurrent Tumors Revealed by an Autopsy-A Case Report and Literature Review

Cristian

Boşoteanu

Aşchie

et al. 2022

Case Reports in Gastrointestinal Medicine

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show abstract

“…The slides were evaluated by a Nikon Eclipse E600 microscope and representative photos were taken from digital whole slide images, obtained with HuronTISSUEScope TM 4000XT scanner. [ 11 ]…”

Section: Case Reportmentioning

confidence: 99%

Proteomics and genomics of a monomorphic epitheliotropic intestinal T-cell lymphoma: An extremely rare case report and short review of literature

et al. 2022

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Rationale: Monomorphic epitheliotropic intestinal T-cell lymphoma, formerly known as enteropathy-associated T-cell lymphoma, is an extremely rare, aggressive peripheral extranodal T-cell lymphoma, that is infrequent in native European and Caucasian populations. The current study presents the clinicopathological features, diagnostic approach, and clinical outcomes of this rare entity of lymphoma and highlights the importance of the early diagnosis of monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL).Patient concerns: Main symptoms and/or important clinical findings: We present the case of a 69-year-old male patient presenting with an abdominal mass, intestinal transit disorder, and weight loss. The abdominal computed tomography (CT) revealed features suggestive of a malignancy. Following clinical and imaging investigations, surgical resection of the small intestine with other areas of involvement has been performed and further to the histopathological examination and immunohistochemical testing are mandatory.Diagnoses and Interventions: Histopathological evaluation of the tumor revealed a proliferation of medium-to largesized monomorphic lymphocytes, with vesicular nuclei, prominent nucleoli, and a moderate amount of clear to pale eosinophilic cytoplasm, with an association of infrequent Reed-Sternberg-like cells. Immunohistochemical assessment of the aforementioned tumor using CD3, CD8, CD5, CD20, and CD30 confirmed the T cell proliferation line and the monomorphic epitheliotropic intestinal T-cell lymphoma diagnosis.Lessons: The current report highlights the importance of early diagnosis of MEITL owing to its poor prognosis and presents histopathological features that help distinguish MEITL from inflammatory bowel diseases and less aggressive T-cell lymphomas.

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AI in Surgery: Navigating Trends and Managerial Implications Through Bibliometric and Text Mining Odyssey

Le,

Tran

2024

Surg Innov

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Background: This research employs bibliometric and text-mining analysis to explore artificial intelligence (AI) advancements within surgical procedures. The growing significance of AI in healthcare underscores the need for healthcare managers to prioritize investments in this technology. Purpose: To assess the increasing impact of AI on surgical practices through a comprehensive analysis of scientific literature, providing insights that can guide managerial decision-making in adopting AI solutions. Research Design: The study analyzes over 6000 scientific articles published since 1990 to evaluate trends and contributions in the field, informing managers about the current landscape of AI in surgery. Study Sample: The research focuses on publications from various influential publishers across North America, Northern Asia, and Eastern & Western Europe, highlighting key markets for AI implementation in surgical settings. Data Collection and Analysis: A bibliometric approach was utilized to identify key contributors and influential journals. At the same time, text-mining techniques highlighted significant keywords related to AI in surgery, aiding managers in recognizing essential areas for further exploration and investment. Results: The year 2022 marked a significant upsurge in publications, indicating widespread AI integration in healthcare. The U.S. emerged as the foremost contributor, followed by China, the UK, Germany, Italy, the Netherlands, and India. Key journals, such as Annals of Surgery and Spine Journal, play a crucial role in disseminating research findings, serving as valuable resources for managers seeking to stay informed. Conclusions: The findings underscore AI’s pivotal role in enhancing diagnostic precision, predicting treatment outcomes, and improving operational efficiency in surgical practices. This progress represents a significant milestone in modern medical science, paving the way for intelligent healthcare solutions and further advancements in the field. Healthcare managers should leverage these insights to foster innovation and improve patient care standards.

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The Role of Artificial Intelligence for Image Analysis in Surgical Pathology

Cited by 3 publications

References 0 publications

Concurrent Tumors Revealed by an Autopsy-A Case Report and Literature Review

Concurrent Tumors Revealed by an Autopsy-A Case Report and Literature Review

Proteomics and genomics of a monomorphic epitheliotropic intestinal T-cell lymphoma: An extremely rare case report and short review of literature

AI in Surgery: Navigating Trends and Managerial Implications Through Bibliometric and Text Mining Odyssey

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