The course and management of pulmonary stenosis depends on two main factors, the degree of obstruction to right ventricular outflow and the presence and extent of an over-riding aorta with a ventricular septal defect. This investigation was undertaken to determine how accurately these points could be decided by study of the heart sounds and murmurs. The pulmonary systolic murmur has long been recognized as the most important sign (Peacock, 1866), but the significance of its duration and graphic form has not been widely appreciated. Little attention has been paid to the first heart sound since Petit in 1902 commented on its snapping quality at the base in some cases. The second heart sound at the pulmonary area has been variously described as accentuated, normal, diminished, or absent: this has been due to failure to differentiate between aortic and pulmonary components of the second sound at the pulmonary area as pointed out by Abrahams and Wood (1951). The present investigation shows that the presence or absence of the pulmonary component and its delay in relation to the aortic component are of considerable help in diagnosis.
METHODSeventy patients with pulmonary valvular or infundibular stenosis were studied. The clinical diagnosis was confirmed by cardiac catheterization or angiocardiography in all, and also by operation in thirty-five and by necropsy in three cases.Auscultation was always carried out by one of us and the intensity of heart sounds and murmurs was graded, the classification of Freeman and Levine (1933) being used for systolic murmurs. Special attention was paid to the first and second heart sounds, and to the intensity and length ofthe systolic murmur. Highfrequency phonocardiograms corresponding to auscultation (Leatham, 1952) were taken in every case, and were repeated in six after operation. Simultaneous recordings were made from the pulmonary and mitral areas together with an electrocardiogram and an indirect carotid pulse tracing in every case, and synchronously with a pressure pulse from the pulmonary artery and right ventricle in eleven cases. The mitral and tricuspid components of the first sound and the ejection sound were identified by methods already described (Leatham, 1954). The aortic component of the second sound was identified by its relation to the dicrotic notch of the carotid tracing allowing for a delay of from 0-02 to 0104 second. The pulmonary component was identified by its maximum intensity at the pulmonary area and by its synchrony with the dicrotic notch of the tracing from the pulmonary artery when this was obtained simultaneously. The two components of the second heart sound were also identified by taking synchronous phonocardiograms from the pulmonary and mitral areas, since only the aortic component is transmitted to the apex (Leatham, 1954).The duration of right ventricular systole was estimated by measuring the time interval between the tricuspid component of the first sound and the pulmonary component of the second. In the same way left ventricular systole was ...