2022
DOI: 10.5593/sgem2022/6.1/s25.17
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The Role of Bacteriorhodopsin in Light Harvesting and Atp Production by Halobacterium Salinarum Cells

Abstract: Halobacterium salinarum is an extremely halophilic marine Gram-negative obligate aerobic archaeon. Despite its name, this is not a bacterium, but rather a member of the domain Archaea, which lives in hypersaline lakes. Bacteriorhodopsin (BRh) is the red retinal-containing protein found in the cell membranes of H. salinarum and is considered a light-activated proton pump that transports protons across the plasma membrane. Bacteriorhodopsin photointermediates have been defined in kinetic and spectroscopic terms … Show more

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“…Stimulation of mitochondrial activity would cause cellular energy metabolism to return to the phenotype characteristic of non-malignant cells and would also promote ROS production by mitochondria, leading to apoptotic cell death of tumour cells [218,296]. We believe, however, that hypoxia causes the breakdown of the triplet states of the biologically active molecules in ECT responsible for the electromagnetic transfer of energy from NADH and FADH 2 to ATP [297]. This hypothesis is also supported by the fact that hypoxia greatly reduces the number of mitochondria in the body's cells [298,299].…”
Section: Discussionmentioning
confidence: 95%
“…Stimulation of mitochondrial activity would cause cellular energy metabolism to return to the phenotype characteristic of non-malignant cells and would also promote ROS production by mitochondria, leading to apoptotic cell death of tumour cells [218,296]. We believe, however, that hypoxia causes the breakdown of the triplet states of the biologically active molecules in ECT responsible for the electromagnetic transfer of energy from NADH and FADH 2 to ATP [297]. This hypothesis is also supported by the fact that hypoxia greatly reduces the number of mitochondria in the body's cells [298,299].…”
Section: Discussionmentioning
confidence: 95%