This research aims to explore the factors that support the success of the 2022 ISDP MSME mentoring program, as well as efforts by the management of the 2022 ISDP MSME mentoring program to maintain the performance of MSMEs during and after the mentoring ends. The research method used is qualitative descriptive research to explore the factors that influencethe success of mentoring MSMEs. Data was obtained using interviews, observation, and documentation methods. Data analysis was carried out in four stages: relevance analysis, content analysis, correlation analysis, and triangulation. Informants were selected using purposive sampling and snowballing methods. Informants consisted of ISDP program managers and MSME mentoring participants. The research results show that the factors supporting the success of the “ISDP” MSME mentoring program consist of 4 factors: mentoring material that suits the needs of MSMEs, availability of mentoring funds or capital, routine monthly business assistance, and sustainability of MSME businesses. Apart from that, it was also found that efforts were made by the ISDP program to maintain the performance of MSMEs, namely by carrying out time management, building ukhuwah, and mapping participants.