The Role of C-Reactive Protein and Albumin Combined Indexes in Acute Cholecystitis

Abstract

Aim
 This study aimed to determine and compare the abilities of the CAR, GPS, and mGPS to predict short-term mortality in patients with acute cholecystitis.
 Materials and Methods
 This retrospective study used the examinations and data of patients who attended the Emergency Department were used. The Statistical Package for Social Sciences (SPSS) software (v.20; Chicago, IL, USA) was used for all statistical analyses. All results with p < 0.05 were considered statistically significant.
 Results
 This study included 269 patients aged 58.3±17.4 years, of which 51% were women. The abilities of CAR, GPS, and mGPS to predict mortality were found to be statistically significant. Their AUC values were 0.73 (0.09–0.98) for CAR with a cut-off value of 3.9 (p = 0.003), 0.72 (0.10–0.97) for GPS with a cut-off value of 2 (p = 0.006), and 0.73 (0.10–0.97) for mGPS with a cut-off value of 2.
 Conclusions
 Inflammatory markers, including CRP and albumin, can predict the prognosis of patients with acute cholecystitis, as in many other diseases.