“…Canthaxanthin is added to food, but it has been reported that the intake of foods with added canthaxanthin can lead to canthaxanthin retinopathy, retinal dystrophy and aplastic anemia (Oosterhuis, Remky, Nijinan, Craandijk & de Wolff, 1989;Sujak, 2009;McGuiness & Beaumont, 1985;Daicker, Schiedt, Adnet & Bermond, 1987;Hennekes, 1986;Bluhm, Branch, Johnston & Stein, 1990). Canthaxanthin is also used as a skin tanning agent in cosmetics (Lober, 1985;Baker & Gunther, 2004).…”