2019
DOI: 10.31857/s0869-56524893313-317
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The role of catecholamines in the development of pathological retina neovascularization in an experimental model of retinopathy of prematurity in rats

Abstract: This work is dedicated to prove our hypothesis that catecholamines and their metabolites play crucial role in development of retinopathy of prematurity, severe disabling fibrovasoproliferative vitreoretinal pathology of premature infants. Research was done on experimental model of retinopathy achieved by hyperohygenation in rats on 7th, 14th, 21st and 30th day of life. Amount of catecholamines and their metabolites in retina of rats was measured by HPLC with electrochemical detection. It was shown that L-DOPA … Show more

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