The role of computed tomography in adult post-mortem examinations: an overview

Jeffery, Amanda

doi:10.1016/j.mpdhp.2010.08.017

Cited by 41 publications

(23 citation statements)

References 55 publications

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“…The identification of patients with vulnerable plaques is difficult and the combination of several sophisticated imaging methods (i.e. OCT/Backscattered IVUS; IVUS/Raman spectroscopy OCToptical coherence tomography; IVUS-intravascular ultrasound) may provide the most information on the presence or absence of disease [8]. Many of these methods cannot be used in the post-mortem setting.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of postmortem MDCT and MDCT-angiography for the investigation of sudden cardiac death related to atherosclerotic coronary artery disease

Michaud

Grabherr

Doenz

et al. 2012

Int J Cardiovasc Imaging

101

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The goal of this study was to evaluate the diagnostic value of postmortem multi-computed tomography (MDCT) and MDCT-angiography for sudden cardiac deaths related to ischemic heart disease. Twenty three cases were selected based on clinical history and the results of native MDCT, multiphase post-mortem CT-angiography and conventional autopsy were compared. Radiological examination showed calcification of coronary arteries in 78% of the cases, most of which were not detailed at autopsy. MDCT-angiography allowed better visualization of the coronary arteries than MDCT and permitted the evaluation of stenoses and occlusions. Of the 14 cases of coronary thrombosis detected at conventional autopsy, 11 were visible as stop of perfusion with CT-angiography and three were found to be partly perfused. One case had an old thrombosis with collateral circulation. One case had a coronary artery postmortem clot found with MDCT-angiography. Coronary artery calcifications are more easily detected and documented with radiological examination than with conventional autopsy. MDCT is of limited diagnostic value for ischemic heart disease. MDCT-angiography, when correctly interpreted, is a reasonable tool to view the morphology of coronary arteries, rule out significant coronary artery stenoses, identify occlusions and direct sampling for histological examination.

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Section: Discussionmentioning

confidence: 99%

“…Authors are currently debating if postmortem radiology should be a complementary examination or if it can be considered as a good replacement for conventional autopsy [8][9][10]. Postmortem MDCT appears to be very useful in demonstrating traumatic lesions.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of postmortem MDCT and MDCT-angiography for the investigation of sudden cardiac death related to atherosclerotic coronary artery disease

Michaud

Grabherr

Doenz

et al. 2012

Int J Cardiovasc Imaging

101

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“…Relatively low maintenance costs, short examination times, and ease of operation make CT a widely used cross-sectional imaging technique in modern postmortem imaging (3). Compared with conventional autopsy, postmortem CT has several advantages, which can lead to important improvements in both research and postmortem investigation (4)(5)(6)(7)(8).…”

mentioning

confidence: 99%

“…Cardiovascular disease is a major cause of unexpected natural death in most developed countries (9), and this limitation decreases the potential of postmortem CT to help diagnose cardiovascular disease. Consequently, the reference standard for investigation of natural death, and particularly cardiovascular death, is considered to be conventional autopsy (2)(3)(4)(5)7).…”

mentioning

confidence: 99%

Postmortem CT Angiography Compared with Autopsy: A Forensic Multicenter Study

Grabherr¹,

Heinemann²,

Vogel³

et al. 2018

Radiology

116

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Purpose: To determine if postmortem computed tomography (CT) and postmortem CT angiography help to detect more lesions than autopsy in postmortem examinations, to evaluate the strengths and weaknesses of each method, and to define their indications. Materials and Methods:Postmortem CT angiography was performed on 500 human corpses and followed by conventional autopsy. Nine centers were involved. All CT images were read by an experienced team including one forensic pathologist and one radiologist, blinded to the autopsy results. All findings were recorded for each method and categorized by anatomic structure (bone, organ parenchyma, soft tissue, and vascular) and relative importance in the forensic case (essential, useful, and unimportant).

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“…The first post-mortem CT (PMCT) was reported in 1983. 1 Since then, the numbers of PMCT examinations have increased significantly through the past years [2][3][4][5][6][7][8][9][10][11] to the point where it has now become a routine investigation in several medicolegal centres all over the world. This may be because of the fact that the handling of a CTscan is relatively easy, data acquisition is rapid and maintenance costs are affordable for some institutes of legal medicine.…”

mentioning

confidence: 99%

Advances in post-mortem CT-angiography

Grabherr¹,

Grimm²,

Domínguez³

et al. 2014

BJR

119

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Performing a post-mortem multidetector CT (MDCT) scan has already become routine in some institutes of forensic medicine. To better visualize the vascular system, different techniques of post-mortem CT-angiography have been explored, which can essentially be divided into partial-and whole-body angiography techniques. Probably the most frequently applied technique today is the so-called multiphase post-mortem CT-angiography (MPMCTA) a standardized method for investigating the vessels of the head, thorax and abdomen. Different studies exist, describing its use for medicolegal investigations, and its advantages as well as its artefacts and pitfalls. With the aim to investigate the performance of PMCTA and to develop and validate techniques, an international working group was created in 2012 called the "Technical Working Group Post-mortem Angiography Methods" (TWGPAM). Beyond its primary perspective, the goals of this group include creating recommendations for the indication of the investigation and for the interpretation of the images and to distribute knowledge about PMCTA. This article provides an overview about the different approaches that have been developed and tested in recent years and an update about ongoing research in this field. It will explain the technique of MPMCTA in detail and give an outline of its indications, application, advantages and limitations.

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The role of computed tomography in adult post-mortem examinations: an overview

Cited by 41 publications

References 55 publications

Evaluation of postmortem MDCT and MDCT-angiography for the investigation of sudden cardiac death related to atherosclerotic coronary artery disease

Evaluation of postmortem MDCT and MDCT-angiography for the investigation of sudden cardiac death related to atherosclerotic coronary artery disease

Postmortem CT Angiography Compared with Autopsy: A Forensic Multicenter Study

Advances in post-mortem CT-angiography

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