The role of diet in acne: facts and controversies

Davidovici, Batya B.; Wolf, Ronni

doi:10.1016/j.clindermatol.2009.03.010

Cited by 46 publications

(33 citation statements)

References 60 publications

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“…23 Similarly, the weather has been known to influence acne prevalence and severity. 24 Our results also did not establish any relationship between acne and diet. However, fasting was observed to be an aggravating factor of acne.…”

supporting

confidence: 54%

Comparison Study on Frequency, Severity and Risk Factors of Acne among Male and Female Medical Students

Mohib¹

2017

jmscr

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supporting

confidence: 54%

Comparison Study on Frequency, Severity and Risk Factors of Acne among Male and Female Medical Students

Mohib¹

2017

jmscr

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“…Currently, evidence does not support a link between chocolate or any other specific food and acne, though few well-designed studies have been undertaken (47).…”

Section: Detrimental Health Effectsmentioning

confidence: 99%

“…Chocolate has been implicated in conditions, such as acne (47) and heart burn or gastroesophageal reflux disease (GERD) (179,282). There is also a common perception that chocolate can be a trigger for migraines (279).…”

Section: Detrimental Health Effectsmentioning

confidence: 99%

Cocoa and Chocolate in Human Health and Disease

Katz

Doughty

Ali

2011

Antioxidants & Redox Signaling

346

256

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Cocoa contains more phenolic antioxidants than most foods. Flavonoids, including catechin, epicatechin, and procyanidins predominate in antioxidant activity. The tricyclic structure of the flavonoids determines antioxidant effects that scavenge reactive oxygen species, chelate Fe2+ and Cu+, inhibit enzymes, and upregulate antioxidant defenses. The epicatechin content of cocoa is primarily responsible for its favorable impact on vascular endothelium via its effect on both acute and chronic upregulation of nitric oxide production. Other cardiovascular effects are mediated through anti-inflammatory effects of cocoa polyphenols, and modulated through the activity of NF-jB. Antioxidant effects of cocoa may directly influence insulin resistance and, in turn, reduce risk for diabetes. Further, cocoa consumption may stimulate changes in redox-sensitive signaling pathways involved in gene expression and the immune response. Cocoa can protect nerves from injury and inflammation, protect the skin from oxidative damage from UV radiation in topical preparations, and have beneficial effects on satiety, cognitive function, and mood. As cocoa is predominantly consumed as energy-dense chocolate, potential detrimental effects of overconsumption exist, including increased risk of weight gain. Overall, research to date suggests that the benefits of moderate cocoa or dark chocolate consumption likely outweigh the risks. Antioxid. Redox Signal. 15, 2779-2811.

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Section: Seborrhea and Acne: Inseparable Players Of The Pathogenic Prmentioning

confidence: 99%

“…However, Davidovici and Wolf [105] pointed out the few studies on humans that have yielded inconsistent results. They concluded that despite the numerous studies mostly of unsatisfactory quality there is a paucity of reliable information on the influence of dietary measures on acne [105]. Bowe et al [106] however considered there is reasonably compelling evidence that a highly glycemic diet may exacerbate acne, the role of ω-3 fatty acids, antioxidants, zinc and vitamin A being unclear.…”

Section: Seborrhea and Acne: Inseparable Players Of The Pathogenic Prmentioning

confidence: 99%

Acne Pathogenesis: History of Concepts

Tilles¹

2014

Dermatology

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From the first reliable descriptions of acne in the early 19th century, dermatologists recognized it as a disease of the pilosebaceous follicle. Until the middle of the 20th century, they hypothesized that seborrhoea, follicular keratosis and microorganisms could be individually responsible for the acne lesions. Inflammation was only regarded as the final and inescapable step of the acne process. Although the importance of these factors has been reevaluated, recent works still regarded them as mandatory. In the 1970s, the onset of isotretinoin dramatically improved acne management. It also provided great opportunities for a better understanding of the pathogenic factors of acne. This study analyzes their genesis and development from the seminal contributions until recent advances.

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The role of diet in acne: facts and controversies

Cited by 46 publications

References 60 publications

Comparison Study on Frequency, Severity and Risk Factors of Acne among Male and Female Medical Students

Comparison Study on Frequency, Severity and Risk Factors of Acne among Male and Female Medical Students

Cocoa and Chocolate in Human Health and Disease

Acne Pathogenesis: History of Concepts

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