The Role of Disordered Proteins in Membrane Curvature Sensing during Endocytosis

Abstract

Due to their ubiquity, versatility, and chemical diversity, lipid bilayers are an increasingly important component of engineered biosensors and biophysical measurement platforms. Bilayers supported on solid substrates are a common design feature of these systems, and the presence of the substrate introduces perturbations in the bilayer structure, affecting both stability and function.