The Role of “Dormant” Mechanisms in Regulation of K/Na Balance in the Rat Cardiac Muscle Cell during Hypoxia

Effect of acute hypoxia on the concentrations of potassium and phosphorus in the cardiomyocyte of a pregnant animal during early organogenesis

“…1). This reaction corresponds to the cascade response of cardiomyocytes to prolonged hypoxia [1][2]9]. Na + / H + exchange compensates for cellular acidosis, which is accompanied by Na + accumulation in the cytoplasm.…”

“…One of the immediate responses of the cardiomyocyte to hypoxia is cell deenergization, which results in cytoplasmic potassium deficiency [1][2] and phosphate release [3,7]. These changes occur during early organogenesis, which is accompanied by episodes of acute hypoxia [5].…”

Electron probe microanalysis of cytoplasmic concentrations of elements in a single cell in culture and suspension

“…The adequacy of the method of "embedded" sections for EPMA was verified on tissues [55,57] and in comparative experiments on preparations of primary cardiomyocyte culture [8,56]. The method was used with lyophilized cryosections of primary culture of cardiomyocytes; data for isolated myocyte were reported [68].…”

“…Tissue sections were analyzed for evaluating sodium distribution in the frog skin epithelium [37], potassium and calcium content in the insect complex eye cell [22], ion compartmentalization in the frog oocyte [23], element concentrations in rat thymocytes [66], and changes in the cytoplasmic concentration of potassium, sodium, and chlorine in myocytes of ischemic rat heart [9][10][11]55].…”