The role of endogenous ligands and biogenic amines in the development of the comorbid course of gastroesophageal reflx disease and chronic obstructive pulmonary inflmmation

Abstract

The paper analyzes the role of endogenous ligands and biogenic amines in the development of the comorbid course of gastroesophageal reflux disease and chronic obstructive pulmonary inflammation. It is shown that the study of the role of inflammation in the development of GERD and COPD led to a new perspective on the mechanisms of damage to target organs in the isolated course of these diseases. This makes it possible to approach from new positions, both the formation of therapy schemes and the development of preventive measures. Key words: gastroesophageal reflux disease, chronic obstructive pulmonary inflammation, pathogenesis, apelin, norepinephrine.