2023
DOI: 10.1038/s41386-023-01766-2
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The role of endogenous opioids in mindfulness and sham mindfulness-meditation for the direct alleviation of evoked chronic low back pain: a randomized clinical trial

Lora Khatib,
Jon G. Dean,
Valeria Oliva
et al.

Abstract: Chronic low back pain (cLBP) is the most prevalent chronic pain condition. There are no treatments that haven been found to directly assuage evoked cLBP. To this extent, mindfulness-meditation is a promising pain therapy. Yet, it is unclear if meditation can be utilized to directly attenuate evoked chronic pain through endogenous opioids. A double-blind, randomized, and placebocontrolled clinical trial with a drug crossover design examined if mindfulness-meditation, as compared to sham mindfulnessmeditation, a… Show more

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