The role of endosonography-guided fine needle aspiration in preoperative restaging in the era of novel neoadjuvant therapies—a literature review

Abstract

Background and Objective: The objective of this literature review is to assess the role and diagnostic performance of endosonography (endobronchial, endoesophageal, and combined endobronchial and endoesophageal ultrasound)-guided fine-needle aspiration in restaging the mediastinum after neoadjuvant therapy in lung cancer. Currently, mediastinal restaging in lung cancer after neoadjuvant therapy is a challenging and controversial issue, and optimal approach remains unclear.Methods: A search was performed in PubMed and Google for relevant studies, reviews and meta-analyses on diagnostic performances of endosonography-guided fine needle aspiration and other methods in restaging stage III lung cancer after neoadjuvant therapy. The articles published in English language between 1998-2021 were assessed.