The COVID-19 epidemic has caused giant influences on people’s life, and China’s communities play an important role in dealing with these major public health events (MPHEs). Community as the grassroots autonomous organization has various significant functions in intervening in MPHEs. The community intervention follows a system which directly influences the anti-epidemic effectiveness. To explore the mechanism, we devise a theoretical system for community intervention, mainly consisting of “organizational structure”, “functional performance” and “internal and external connections”. Questionnaire surveys, the chi-square test, the independent sample T-test, and principal component analysis are used to identify the characteristics of Inner Mongolia Autonomous Region’s (Inner Mongolia) community intervention. Through the empirical research, it is verified that the community intervention in MPHEs is the combination of “the structural response of the organization”, “the performance of the community’s own function”, and “the establishment of internal and external connections”. The central Inner Mongolia delivers the best performance in community intervention compared to eastern Inner Mongolia and western Inner Mongolia. The urban communities commonly perform better than that in the agricultural and pastoral areas. The built system and findings could provide a guidance for future community to improve its intervention capability.