The Role of Ferritin and Vitamin D Levels in Telogen Effluvium

Gürel, Gülhan; Karadöl, Müjgan; Çölgeçen, Emine

doi:10.5336/dermato.2017-56970

Cited by 5 publications

(6 citation statements)

References 13 publications

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“…The number of patients with the highest abnormalities in all parameters was observed in TE and females; therefore, we particularly suggest examining patients with TE and female patients first. More studies had been reported on laboratory abnormalities in TE, and they may also support our suggestion [ 12 , 17 , 17 , 27 – 29 ]. After vitamin D deficiency in both sexes, investigation ferritin and hemoglobin deficiency in females and vitamin B12 deficiency in males may be recommended.…”

Section: Discussonsupporting

confidence: 89%

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Öner¹,

Akdeniz²

2021

Turk J Med Sci

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Background/aim: Vitamins and minerals are thought to play an essential but not entirely clear role in developing, preventing, and treating nonscarring alopecia. Telogen effluvium, androgenetic alopecia, and alopecia areata are the most common forms of nonscarring alopecias. We would like to present a different perspective on laboratory abnormalities in patients with nonscarring alopecia. Materials and methods:A total of 467 patients (287 females, 180 males) were included retrospectively. 160 patients in the telogen effluvium group, 101 patients in the androgenetic alopecia group, 99 patients in the alopecia areata group, and 107 patients in the hair loss group (patients who could not be diagnosed with any nonscarring alopecia and wanted to have an analysis due to the complaint of hair loss). Sociodemographic data, diagnostic distribution, and laboratory findings (hemoglobin, ferritin, vitamin B12, vitamin D, and TSH) were evaluated and compared. Results:The most common diagnosis was telogen effluvium in females and androgenetic alopecia in males. In women, hemoglobin (12.2% vs. 1.1%) and ferritin deficiencies (22.3% vs. 8.9%) were significantly higher than in men (p<0.001, p<0.001) Ferritin, hemoglobin, and vitamin B12 levels were significantly lower, and the number of patients with vitamin D, ferritin, hemoglobin and vitamin B12 deficiencies were significantly higher in the telogen effluvium group compared to the other groups. Laboratory abnormalities were detected least in the hair loss group.2 Conclusions:The number of patients with the highest abnormalities in all parameters was observed in the telogen effluvium group and females; therefore, we mainly suggest examining female patients with telogen effluvium first. We may prefer not to immediately investigate the laboratory abnormalities and follow up patients with some treatments in the hair loss group.

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Section: Discussonsupporting

confidence: 89%

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Öner¹,

Akdeniz²

2021

Turk J Med Sci

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“…10,15 After the immunomodulatory effect of vitamin D was demonstrated, its potential role has been studied in many areas of medicine including skin and hair diseases. 10,[12][13][14][15][16][17][18][19][20][21][22][23][24] It was demonstrated that keratinocytes are capable of metabolizing vitamin D to the active form. 25 Other cells including macrophages and dendritic cells are also capable of synthesizing the active form of vitamin D, and this process is predominantly regulated by immune signals.…”

Section: Discussionmentioning

confidence: 99%

“…To our knowledge there are 4 prospective case control studies evaluating vitamin D levels in TE patients. 4,[21][22][23] In 3 of these studies vitamin D levels were found to be significantly lower in TE patients than controls. 21,23,24 Contrary to these studies, Karadağ et al reported an interesting result that they found vitamin D levels higher in patients with TE.…”

Section: Discussionmentioning

confidence: 99%

“…There are also studies evaluating the effect of vitamin D on hair diseases. 4,[16][17][18][19][20][21][22][23][24] To our knowledge there are limited number of studies investigating the relationship between TE and vitamin D and results of these studies were contradictory. 4,[21][22][23][24] We planned this study to evaluate the vitamin D levels in TE patients and to investigate whether there is a relationship between vitamin D status and TE.…”

Section: Evaluation Of Vitamin D Levels In Chronic Telogen Effluvium mentioning

confidence: 99%

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Evaluation of Vitamin D Levels in Chronic Telogen Effluvium Patients

Çifci¹

2018

Turkiye Klinikleri J Dermatol

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“…The year of publication ranged from 1988 to 2019. One study was published in German [14], 2 in Turkish [15,16], and the rest in English. Articles published in languages other than English were addressed using language translation agency.…”

Section: Study Characteristicsmentioning

confidence: 99%

Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis

Treister-Goltzman

Yarza

Peleg

2021

Skin Appendage Disord

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Background: There is no clear-cut evidence in the existing medical literature of an association between iron deficiency and nonscarring alopecia. Objective: The objective of the study was to conduct a systematic review of the medical literature on the prevalence of iron deficiency in women with nonscarring alopecia and compare their ferritin levels with those of women without this condition. Methods: The electronic databases PubMed, Scopus, and Web of Science were searched between June 15, 2019, and July 24, 2019. Studies that evaluated the prevalence of iron deficiency in women with nonscarring alopecia and/or compared ferritin levels in women with and without this condition were entered into the meta-analysis. Thirty-six of 928 identified studies entered the systematic meta-analysis. The meta-analysis was performed using the random-effects method. Results: The overall number of participants was 10,029. The prevalence of ferritin levels from 10 to 15 ng/dL and below was 21% (12; 29). Women with nonscarring alopecia had lower ferritin values at MD = −18.51 ng/dL (−25.85; −11.16, p < 0.01). Conclusion: Women with hair loss can benefit from higher ferritin levels.

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The Role of Ferritin and Vitamin D Levels in Telogen Effluvium

Cited by 5 publications

References 13 publications

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Nonscarring scalp alopecia: Which laboratory analysis should we perform on whom?

Evaluation of Vitamin D Levels in Chronic Telogen Effluvium Patients

Iron Deficiency and Nonscarring Alopecia in Women: Systematic Review and Meta-Analysis

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