The role of fine needle aspiration biopsy in deep lobe parotid tumors: Comparison of preoperative cytology and postoperative histopathologic results

Seyhun, Nurullah; Doğan, Uğur; Calis, Zeynep Asli Batur; Kaya, Mehmet; Hasçiçek, Seyhan Özakkoyunlu; Turgut, Suat

doi:10.1016/j.amjoto.2020.102590

Cited by 15 publications

(16 citation statements)

References 14 publications

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“…Another study reported that (78.4%) of the patients, tumor was reported as benign and in (21.6%) patients FNAB diagnosis was suspicious for malignancy, malignant or non-diagnostic. In final histopathologic diagnosis, 42 of the tumors were benign and 9 were malignant [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

Role of fine needle aspiration in malignant parotid tumors at a single-center experience: A retrospective cohort study

Alwagdani

Alhejaili

Alanzi

et al. 2021

Annals of Medicine &Amp; Surgery

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Background Parotid gland tumors are mostly benign with good prognosis. On the other hand, malignant tumors of the parotid gland often have poor prognosis and metastasize. Mucoepidermoid carcinoma is the most common cancer in the parotid gland accounting for nearly 40–50% of the cases. Therefore, it is important to define the role of fine needle aspiration in differentiating between different types of parotid malignancies. Method This is a retrospective chart review study that was done on 49 consecutive patients who underwent parotid surgeries in King Fahad Armed Forces Hospital in Jeddah, Saudi Arabia, between Jan 2003 and Feb 2020. The records of 49 patients were obtained, fine needle aspiration and pathology reports were reviewed to define the role of fine needle aspiration in diagnosing malignant parotid tumors by calculating the sensitivity, specificity, positive predictive value, and negative predictive value. Results Retrospective analysis of 39 cases revealed that there was one case which was diagnosed for cancer was missed by fine needle aspiration. Meanwhile, six cases were diagnosed as malignant lesions using both fine needle aspiration and histopathology. Furthermore, 30 cases were determined benign based on fine needle aspiration and histopathology. The sensitivity of fine needle aspiration for detecting malignancy was 85.7%, specificity was 93.8%. positive predictive value of 75% and negative predictive value of 96.7%. Conclusion Fine needle aspiration is highly sensitive and specific for parotid tumors. We support the role of pre-operative FNA for all parotid tumors as its accurate in differentiating between benign and malignant lesions.

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Section: Discussionmentioning

confidence: 99%

Role of fine needle aspiration in malignant parotid tumors at a single-center experience: A retrospective cohort study

Alwagdani

Alhejaili

Alanzi

et al. 2021

Annals of Medicine &Amp; Surgery

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“…Nevertheless, diagnostic challenges in salivary gland FNAC (SG-FNAC) are well documented, particularly in several cases of neoplasms. FNAC can distinguish many benign tumors and can usually differentiate between low-and high-grade carcinomas [1][2][3][4][5][6][7][8][9][10]. Based upon the cytologic interpretation, all malignant tumors and several benign tumors are typically treated by surgical excision.…”

Section: Introductionmentioning

confidence: 99%

“…In this regard, the correct diagnosis of malignant entities is a crucial element in determining the extent of surgery including preservation of the facial nerve in the case of parotid tumors and indications for neck dissection. However, it is also important to underline that specific benign entities such as certain pleomorphic adenomas and Warthin tumors are associated with a non-surgical management hinged on clinical follow-up and imaging depending upon patient wishes and health status [1][2][3][4][5][6][7][8].…”

Section: Introductionmentioning

confidence: 99%

“…Several studies demonstrated that the rate of malignancy varies depending upon the size of the mass and the location. For example, the ROM increases from 20-25% in the parotid gland, to 40-50% in the submandibular gland, and to 50-81% in the sublingual and minor salivary glands [5][6][7][8]. Despite the advantages of SG-FNAC, several authors pointed to the wide range of sensitivity and specificity depending upon a variety of factors including FNA technique, cytologic preparation, experience, lesional heterogeneity, and cystic component.…”

Section: Introductionmentioning

confidence: 99%

“…Despite the advantages of SG-FNAC, several authors pointed to the wide range of sensitivity and specificity depending upon a variety of factors including FNA technique, cytologic preparation, experience, lesional heterogeneity, and cystic component. It has been demonstrated that SG-FNAC lacks specificity in precisely classifying the tumor as a specific subtype which is also linked with the biphasic nature of several malignant salivary lesions [1][2][3][4][5][6][7][8]. Furthermore, the accuracy of SG-FNA is high for the diagnosis of most common salivary gland tumors such as pleomorphic adenoma (Figure 1A,B) and Warthin tumors.…”

Section: Introductionmentioning

confidence: 99%

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The Milan System, from Its Introduction to Its Current Adoption in the Diagnosis of Salivary Gland Cytology

Rossi

2021

JMP

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Salivary gland masses are often encountered in the everyday practice of cytopathology. It is commonly known that the cytologic interpretation of these lesions can pose diagnostic problems due to overlapping cytomorphologic features. Fine needle aspiration (FNA) of salivary lesions shows good to excellent sensitivity and specificity in differentiating a neoplastic from a non-neoplastic process and in diagnosing common tumors such as pleomorphic adenoma. However, its value is limited in diagnosing specific neoplastic entities especially those with well-differentiated morphology. In light of this gap, an international group of pathologists has proposed a management-oriented, tiered classification for reporting salivary gland FNA specimens, “The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC)”. Similar to other classification systems, the MSRSGC scheme comprises six diagnostic categories, which were linked with a specific risk of malignancy (ROM) and management. In this review article, the author evaluated the published literature on FNA in diagnosing salivary gland lesions with the adoption of the Milan system since its introduction in the daily practice of salivary cytopathology.

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Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence

Levyn,

Subramanian,

Eagan

et al. 2024

Head & Neck

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BackgroundPleomorphic adenoma (PA) is a common parotid tumor, yet due to the relative rarity of deep lobe PA (DLPA), there is a paucity of information about its clinical presentation and surgical outcomes.MethodsWe reviewed the charts of patients with previously untreated parotid PA between the years 1990 and 2015. Clinical parameters and surgical outcomes were compared between superficial lobe PA (SLPA) and DLPA.ResultsThe cohort comprised 147 cases of DLPA and 222 cases of SLPA. DLPA were larger (median 2.6 cm vs. 2.0 cm, p < 0.001), more often discovered incidentally on imaging (33%, n = 48) and had unique presentations (pharyngeal mass, dysphagia, otalgia). Postsurgical complications were more frequently observed in DLPA (41% vs. 30% in SLPA, p = 0.025), mainly transient facial nerve weakness. DLPA also showed higher recurrence rates (n = 6, 4.1% vs. n = 1, 0.4%, p = 0.016).ConclusionsParotidectomy for DLPA carries a higher risk of complications and recurrence compared to SLPA.

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The role of fine needle aspiration biopsy in deep lobe parotid tumors: Comparison of preoperative cytology and postoperative histopathologic results

Cited by 15 publications

References 14 publications

Role of fine needle aspiration in malignant parotid tumors at a single-center experience: A retrospective cohort study

Role of fine needle aspiration in malignant parotid tumors at a single-center experience: A retrospective cohort study

The Milan System, from Its Introduction to Its Current Adoption in the Diagnosis of Salivary Gland Cytology

Parotidectomy for deep lobe pleomorphic adenomas is associated with higher rates of complications and recurrence

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