The role of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) in staging and restaging of patients with uterine sarcomas: a systematic review

Mattoni, Susanna; Paccagnella, Andrea; Fanti, Stefano

doi:10.21037/gpm-20-76

Gynecol Pelvic Med

2022

DOI: 10.21037/gpm-20-76

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The role of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) in staging and restaging of patients with uterine sarcomas: a systematic review

Susanna Mattoni¹,

Andrea Paccagnella²,

Stefano Fanti³

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2024

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Diagnostic role and prognostic impact of positron emission tomography/computed tomography in patients treated for uterine corpus cancer

Stojiljkovic,

Sobic-Saranovic,

Odalovic

et al. 2024

Srp Arh Celok Lek

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Introduction/Objective. The goal of our research was to evaluate diagnostic and prognostic role of positron emission tomography/computed tomography (PET-CT) in patients previously treated for uterine cancer and compare it to conventional imaging methods (CIM). Methods. We analyzed 37 patients examined on PET-CT for follow-up or suspicion of uterine cancer recurrence, and who were previously treated with surgery and/or chemoradiotherapy. All patients underwent computed tomography or magnetic resonance imaging prior to PET-CT, and were followed-up for at least one year. Results. PET-CT showed sensitivity, specificity and diagnostic accuracy in uterine cancer relapse detection of 96.3%, 70% and 89.2%, while those values for CIM were 92.6%, 40% and 78.4 %, respectively. Correlation of PET-CT and CIM findings was 78% (29/37). In 13 out of 25 true positive patients on CIM, PET-CT found greater number of active sites missed by conventional imaging. Positive findings on PET-CT were associated with shorter progression free survival (p = 0.023, logrank test). Conclusion. PET-CT constitutes an important diagnostic method in management of recurrent cancer of uterine corpus, demonstrating high sensitivity and accuracy. In comparison to CIM, PET-CT can discover larger number of active tumor sites, and also shows better specificity. PET-CT positive patients have worse prognosis with shorter progression free survival.

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Diagnostic role and prognostic impact of positron emission tomography/computed tomography in patients treated for uterine corpus cancer

Stojiljkovic,

Sobic-Saranovic,

Odalovic

et al. 2024

Srp Arh Celok Lek

View full text Add to dashboard Cite

show abstract

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The role of fluorine-18-fluorodeoxyglucose-positron emission tomography/computed tomography (18F-FDG-PET/CT) in staging and restaging of patients with uterine sarcomas: a systematic review

Cited by 1 publication

References 31 publications

Diagnostic role and prognostic impact of positron emission tomography/computed tomography in patients treated for uterine corpus cancer

Diagnostic role and prognostic impact of positron emission tomography/computed tomography in patients treated for uterine corpus cancer

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