2010
DOI: 10.1111/j.1439-0272.2009.01025.x
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The role of food supplementation in the treatment of the infertile couple and for assisted reproduction

Abstract: Couple infertility commonly results from the synergistic negative influence of several factors. External factors, related to life-style and environmental exposure, reinforce the effects of congenital or acquired damage through direct toxicity, hormone disruption and overload of reactive oxygen species. Combating obesity, correcting inappropriate diet, and banning the abuse of tobacco and alcohol are part of the integrated approach of the infertile couple. Nutraceuticals are judiciously formulated food suppleme… Show more

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Cited by 27 publications
(28 citation statements)
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References 123 publications
(109 reference statements)
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“…Currently, it is seldom added to the over-the-counter preparation for male infertility treatment. However it should be strengthening the concept that vitamin A has been shown to be toxic and may be teratogenic in higher dose [106, 107]. …”
Section: Antioxidantsmentioning
confidence: 99%
See 1 more Smart Citation
“…Currently, it is seldom added to the over-the-counter preparation for male infertility treatment. However it should be strengthening the concept that vitamin A has been shown to be toxic and may be teratogenic in higher dose [106, 107]. …”
Section: Antioxidantsmentioning
confidence: 99%
“…There is evidence for sperm parameters amelioration after one month of treatment [117], but longer period of treatment is also reported [116]. The dose of vitamin C must, however, is not excessive because high doses may act as a prooxidant, particularly in persons with the haptoglobin type 2- 2 [106, 107]. …”
Section: Antioxidantsmentioning
confidence: 99%
“…In addition, many recent studies report that inappropriate dietary habits (such as meal skipping or false dieting), low intake of antioxidants, and nutrient deficiencies have been observed in male factor infertility. 25,28,[47][48][49][50] The aim of this study was to systematically review published studies that investigated the relationship between nutrition, diet, or food compounds and male factor infertility. As far as can be determined, this is the first systematic review of studies that examined the relation between nutrition or dietary compounds and male infertility.…”
Section: Introductionmentioning
confidence: 99%
“…There is evidence for sperm parameters amelioration after one month of treatment [51], but longer period of treatment is also reported [49]. The dose of vitamin C must, however, is not excessive because high doses may act as a prooxidant, particularly in persons with the haptoglobin type 2-2 [52].…”
Section: Vitamin C (Ascorbic Acid)mentioning
confidence: 97%
“…Altogether, these findings suggest that vitamin E could be a therapeutic choice for the treatment of male infertility. However, we would emphasize that, besides their interesting antioxidant properties, vitamin E analogs, especially tocopheryl succinate, can exert adverse effects on gap junctional intercellular communication, which could explain their controversial effects in spermatogenesis [52].…”
Section: Vitamin Ementioning
confidence: 99%