The Role of Fructose in Public Health and Obesity

Carvalho, Carla Torres; Souza, Maria Zélia de; Arbex, Nawal; Rodrigues, Luciana de Souza Rodrigues de Souza Corrêa; Sá, Diana Aristótelis Rocha de; Sá, Larissa Bianca Paiva de Sá de Cunha; Arbex, Alberto Krayyem

doi:10.4236/health.2018.104035

Cited by 6 publications

(8 citation statements)

References 14 publications

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“…The World Health Organization (WHO) called for a limitation of free sugar [ 17 ], as the consumption of refined sugar would result in a reduction of nutrient density, especially the excessive consumption of fructose from the sugar-sweetened beverages concerning a series of adverse health outcomes [ 18 , 19 , 20 ]. However, the sugar in a reasonable amount of fruit is not a concern, as fruit consumption increases the intake of phytochemicals, potassium and dietary fiber, which are beneficial to the prevention of cardiovascular diseases [ 21 , 22 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

Both Isocarbohydrate and Hypercarbohydrate Fruit Preloads Curbed Postprandial Glycemic Excursion in Healthy Subjects

Fan

Liu

et al. 2021

Nutrients

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This study aimed to investigate the impact of fruit preloads on the acute postprandial glycemic response (PGR) and satiety response of a rice meal in healthy female subjects based on iso-carbohydrate (IC) and hyper-carbohydrate (HC) contents, respectively. The IC test meals including (1) rice preload (R + 35R), (2) orange preload (O + 35R), (3) apple preload (A + 35R) and (4) pear preload (P + 35R), contained 50.0 g available carbohydrates (AC) where the preload contributed 15.0 g and rice provided 35.0 g. The HC meals included (1) orange preload (O + 50R), (2) apple preload (A+50R) and (3) pear preload (P + 50R), each containing 65.0 g AC, where the fruits contributed 15.0 g and rice provided 50.0 g. Drinking water 30 min before the rice meal was taken as reference (W + 50R). All the preload treatments, irrespective of IC or HC meals, resulted in remarkable reduction (p < 0.001) in terms of incremental peak glucose (IPG) and the maximum amplitude of glycemic excursion in 180 min (MAGE0–180), also a significant decrease (p < 0.05) in the area of PGR contributed by per gram of AC (AAC), compared with the W + 50R. Apple elicited the lowest PGR among all test meals, as the A + 35R halved the IPG and slashed the incremental area under the curve in 180 min (iAUC0–180) by 45.7%, while the A + 50R reduced the IPG by 29.7%, compared with the W + 50R. All the preload meals and the reference meal showed comparable self-reported satiety in spite of the difference in AC. In conclusion, pre-meal consumption of three fruits effectively curbed post-meal glycemia even in the case of a 30% extra carbohydrate load.

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Section: Introductionmentioning

confidence: 99%

Both Isocarbohydrate and Hypercarbohydrate Fruit Preloads Curbed Postprandial Glycemic Excursion in Healthy Subjects

Fan

Liu

et al. 2021

Nutrients

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“…The World Health Organization report [10] and dietary guidelines of many countries called for a limitation of added sugar in daily diet [11][12][13] as the inclusion of added sugars in the diet would lead to a decrease of nutrition density, with fructose overconsumption being of particular concern [14][15][16]. However, fruit consumption is encouraged by health professionals as it is conducive to the prevention of cardiovascular diseases by providing antioxidants, potassium, and dietary fiber [17,18].…”

Section: Introductionmentioning

confidence: 99%

Apple Preload Halved the Postprandial Glycaemic Response of Rice Meal in Healthy Subjects

Zhao

Wang

et al. 2019

Nutrients

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This study aimed to investigate the possible glycemic effect of apple preload on acute postprandial glycemic responses (GRs) of a following rice meal, comparing with its co-ingestion counterpart and an apple sugar solution preload, based on equal carbohydrates intake. In a randomized crossover trial, 18 healthy female subjects consumed (1) rice, (2) co-ingestion of apple and rice (A+R), (3) apple preload and rice (PA+R), and (4) rice with sugar solution preload (same sugar profile as in apple) (PSS+R). Acute postprandial GR tests and subjective satiety tests were carried out for each test food. Compared with rice reference, the PA+R achieved a 50% reduction of the iAUC0-120, a 51.4% reduction of the average peak value, and a 52.6% reduction of glycemic excursion in 240 min, while the PSS+R showed 29.7% and 31.6% reduction of peak value and glycemic excursion, respectively. No significant differences were found between R and PA+R in any of the satiety characteristics. Compared with rice control, apple preload of 15 g available carbohydrates remarkably lowered the acute postprandial GR without negative effect on satiety. The sugar component may partly contribute to the glycemic suppressing effect of the apple preload.

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“…Today, two types of soft drinks are being used; regular soft drinks which are sweet with sugar (fructose) and diet soft drinks which are sweet with noncaloric sweet (aspartame) [41]. Fructose is sweet and cheap, therefore, it is used in commercial drinks and sweets [42]. Worldwide, soft drinks are the leading cause for added sugar in the diet.…”

Section: Role In Non-alcoholic Fatty Liver Diseasementioning

confidence: 99%

“…Worldwide, soft drinks are the leading cause for added sugar in the diet. Recent studies suggest that intake of fructose through soft drinks increases the risk of obesity, induced insulin resistance and other diseases [42][43][44].…”

Section: Role In Non-alcoholic Fatty Liver Diseasementioning

confidence: 99%

An Overview of Effects of Carbonated Drinks

Zahra

Shoaib

Iqbal

2019

Natl. j. health sci.

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Soft drinks are those drinks which do not contain alcohol. These soft drinks are either carbonated or non-carbonated soft drinks. Carbonated soft drinks are consumed widely across the globe. Today, when people are becoming more health conscious, concerns are being raised regarding the impact of carbonated soft drinks on health. When discussing the effects of carbonated soft drinks on health carbon dioxide, phosphoric acid and sugar are of main concern. Most carbonated beverages have acidic pH which results in gastroesophageal reflux disease (GERD) like symptoms. The phosphoric solution in these beverages is powerful enough to cause human teeth to become soft. The caffeine present in colas is known to be a hazardous factor for osteoporosis. When taken after a period of dehydration, the sugar in these beverages is known to cause more renal injury then plain water. The sugar content in these beverages may lead to lipids production in the body and result in obesity, hypertension, non-alcoholic fatty liver disease (NAFLD), and pancreatic cancer. Hence, it is necessary to monitor diet and focus on natural and healthy beverages.

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The Role of Fructose in Public Health and Obesity

Cited by 6 publications

References 14 publications

Both Isocarbohydrate and Hypercarbohydrate Fruit Preloads Curbed Postprandial Glycemic Excursion in Healthy Subjects

Both Isocarbohydrate and Hypercarbohydrate Fruit Preloads Curbed Postprandial Glycemic Excursion in Healthy Subjects

Apple Preload Halved the Postprandial Glycaemic Response of Rice Meal in Healthy Subjects

An Overview of Effects of Carbonated Drinks

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