The role of guidance in delivering cardiac resynchronization therapy: A systematic review and network meta-analysis

Mehta, Vishal; Ayis, Salma; Elliott, Mark K.; Widjesuriya, Nadeev; Kardaman, Nuha; Gould, Justin; Behar, Jonathan M.; Chiribiri, Amedeo; Razavi, Reza; Niederer, Steven; Rinaldi, Christopher A.

doi:10.1016/j.hroo.2022.07.005

Cited by 4 publications

(2 citation statements)

References 39 publications

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“…Hence, our meta-analysis with additional data from most included RCTs provides an extended and comprehensive perspective. The most recent meta-analysis is not in agreement with our results, 22 which may be due to diverse study selection criteria. We decided only to include fully published RCTs, while the previous meta-analysis prioritized to also include data from three abstracts; one with preliminary data from the recently published Raise CRT study, 14 and two unpublished studies.…”

Section: Discussioncontrasting

confidence: 73%

Targeted left ventricular lead positioning to the site of latest activation in cardiac resynchronization therapy: a systematic review and meta-analysis

Fyenbo,

Bjerre,

Frausing

et al. 2023

Europace

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Aims Several studies have evaluated the use of electrically- or imaging-guided left ventricular (LV) lead placement in cardiac resynchronization therapy (CRT) recipients. We aimed to assess evidence for a guided strategy that targets LV lead position to the site of latest LV activation. Methods and results A systematic review and meta-analysis was performed for randomized controlled trials (RCTs) until March 2023 that evaluated electrically- or imaging-guided LV lead positioning on clinical and echocardiographic outcomes. The primary endpoint was a composite of all-cause mortality and heart failure hospitalization, and secondary endpoints were quality of life, 6-min walk test (6MWT), QRS duration, LV end-systolic volume, and LV ejection fraction. We included eight RCTs that comprised 1323 patients. Six RCTs compared guided strategy (n = 638) to routine (n = 468), and two RCTs compared different guiding strategies head-to-head: electrically- (n = 111) vs. imaging-guided (n = 106). Compared to routine, a guided strategy did not significantly reduce the risk of the primary endpoint after 12–24 (RR 0.83, 95% CI 0.52–1.33) months. A guided strategy was associated with slight improvement in 6MWT distance after 6 months of follow-up of absolute 18 (95% CI 6–30) m between groups, but not in remaining secondary endpoints. None of the secondary endpoints differed between the guided strategies. Conclusion In this study, a CRT implantation strategy that targets the latest LV activation did not improve survival or reduce heart failure hospitalizations.

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Section: Discussioncontrasting

confidence: 73%

Targeted left ventricular lead positioning to the site of latest activation in cardiac resynchronization therapy: a systematic review and meta-analysis

Fyenbo,

Bjerre,

Frausing

et al. 2023

Europace

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“…Una mejoría en la FEVI significativa en el grupo guiado por imagen (DMP 3.25%; IC95%; 1.80; 4.70) 134 . Estos mismos hallazgos fueron replicados por Mehta et al en 2022 en donde reportó mejores desenlaces en pacientes en los que su dispositivo TRC fue colocado guiado mediante estudios de imagen 135 .…”

Section: Revisión De La Literatura Y Análisisunclassified

Guía mexicana de práctica clínica para el diagnóstico y el tratamiento de la insuficiencia cardiaca

Pavía-López,

Magaña-Serrano,

Cigarroa-López

et al. 2024

ACM

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La insuficiencia cardiaca crónica sigue siendo unas de las principales causas de afectación en el funcionamiento y en la calidad de vida de las personas que la presentan, así como una de las primeras causas de mortalidad en nuestro país y en todo el mundo. México tiene una alta prevalencia de factores de riesgo para desarrollar insuficiencia cardiaca, tales como hipertensión arterial, diabetes y obesidad, lo que hace imprescindible contar con un documento basado en la evidencia que brinde recomendaciones a los profesionales de la salud involucrados en el diagnóstico y el tratamiento de estos pacientes.

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Role of speckle tracking echocardiography beyond current guidelines in cardiac resynchronization therapy

Sperlongano,

Benfari,

Ilardi

et al. 2024

International Journal of Cardiology

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The role of guidance in delivering cardiac resynchronization therapy: A systematic review and network meta-analysis

Cited by 4 publications

References 39 publications

Targeted left ventricular lead positioning to the site of latest activation in cardiac resynchronization therapy: a systematic review and meta-analysis

Targeted left ventricular lead positioning to the site of latest activation in cardiac resynchronization therapy: a systematic review and meta-analysis

Guía mexicana de práctica clínica para el diagnóstico y el tratamiento de la insuficiencia cardiaca

Role of speckle tracking echocardiography beyond current guidelines in cardiac resynchronization therapy

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