The role of headache chronicity among predictors contributing to quality of life in patients with migraine: a hospital-based study

Abstract

BackgroundHeadache chronicity has been known to elicit deleterious effects on quality of life (QOL). We evaluated the contribution of headache chronicity to QOL in relation to clinical, psychiatric, and psychosocial variables in patients with migraine.MethodsSubjects were recruited from a headache clinic and completed self-report questionnaires including the Migraine Disability Assessment (MIDAS), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), and Migraine-Specific Quality of Life (MSQoL). We obtained predictors of MSQoL by multiple regression analyses. A path analysis model was constructed to analyze interrelationships between the variables.ResultsAmong 251 eligible patients, 183 (72.9%) had episodic migraine (EM) and 68 (27.1%) had chronic migraine (CM). Patients with CM had more serious clinical, psychiatric, and poor QOL than did patients with EM. The strongest predictor of the MSQoL score in all patients with migraine was the BDI score (β = -0.373, p < 0.001), followed by the MIDAS score (β = -0.223, p < 0.001), female gender (β = -0.192, p < 0.001), attack duration (β = -0.159, p = 0.001), and headache chronicity (β = -0.130, p = 0.012). Headache chronicity had a direct effect on the MSQoL score and exerted an indirect effect on the MSQoL score through the MIDAS and the BDI scores.ConclusionsChronic migraine appears to impair QOL directly as well as indirectly by provoking disability and depression.

Current concepts in pseudotumor cerebri

“…The 36-Item Short Form Health Survey was used to quantify general health; the National ], and half of the patients had either constant or daily headaches. Even after successful treatment, many IIH patients develop chronic headaches [23], which can have a prolonged impact on QOL [24]. TVOs significantly impact vision-specific QOL [9 & ].…”

Quality of life in idiopathic intracranial hypertension at diagnosis

“…Chronic migraine and chronic headaches associated with medication overuse are associated with worse QOL both directly and indirectly by worsening depression. 20 As is the case in patients with chronic migraine, 21,22 headache seems to be a direct significant contributor to lower QOL in patients with IIH. In fact, the HIT-6 score was associated with every SF-36 subscale.…”

Psychological Factors Associated With Chronic Migraine and Severe Migraine‐Related Disability: An Observational Study in a Tertiary Headache Center

“…Several studies suggest that increases in depression and anxiety symptoms are associated with higher levels of migraine-related disability, [12][13][14] although only a few have evaluated these relationships in tertiary care headache centers. [15][16][17][18] Headache-related cognitions (catastrophizing) and beliefs (locus of control) are postulated to influence the development of chronic migraine, and migraine-related disability. A few studies have demonstrated relationships between higher pain catastrophizing and increased frequency and duration of migraine attacks, 19 higher intensity of headache pain, 20 and impairments in functioning and quality of life; 21 however, none of these studies evaluated people with migraine presenting for routine clinical care.…”