The role of hollow magnetic nanoparticles in drug delivery

Abstract

The increasing number of scientific publications focusing on nanomaterials in the biomedical field indicates growing interest from the broader scientific community.

Synthesis, Properties and Applications of Magnetic Nanoparticles and Nanowires—A Brief Introduction

“…Magnetic particles of different size (nano-and micro-) and various composition resulting in different magnetization (superparamagnetic and ferromagnetic) have found numerous applications in biotechnology [1] and medicine [2][3][4][5]. Particularly, they are used for magneto-controlled targeting (delivering drugs [6,7], genes [8], radiopharmaceuticals [9]), in magnetic resonance imaging [10], in various diagnostic applications [11], for biosensing [12] (e.g., immunoassays [13]), RNA and DNA purification [14], gene cloning, cell separation and purification [15]. Magnetic nano-species with complex topology (e.g., nanorods, nanowires and nanotubes) [16] have been used in numerous nano-technological devices, including tunable micro-fluidic channels with magnetic control [17], data storage units in nano-circuits [18], and magnetized nano-tips for magnetic force microscopes [19].…”

Surface Compositional Change of Iron Oxide Porous Nanorods: A Route for Tuning their Magnetic Properties

“…Iron oxides attract considerable attention due to their many physical properties, which vary greatly among different phases and represent the key to their successful use in a wide array of applications, from hyperthermia, magnetic resonance imaging and drug delivery, to magnetic separation, catalysis and magnetic data storage [1][2][3][4][5][6][7]. Given the richness of the iron/oxygen phase diagram [8], enhancing the performance of any iron oxide phase for such diverse purposes translates into the necessity to master the production of particles of controlled composition, size and shape in order to control the physical features that drive each particular response.…”

γ‐Fe2O3@SiO2‐EC‐ZnII: A Magnetic Recyclable Nanocatalyst for the Synthesis of Spiro[indoline‐3, 9′‐xanthene]trione Derivatives in Aqueous Media

“…Therefore, it is not surprising that a considerable interest in the synthesis of spirooxindole (especially spiro[indoline‐3, 9′‐xanthene]trione) derivatives has been grown recently . Although, there are a few methods in the literature for the synthesis of spiro[indoline‐3, 9‐xanthene]trione derivatives from isatin and dimedone . During last few years, the sustainable development of synthetic methodologies (with less environmental hazards) as a great challenge for chemical and medicinal researches has been provided selective access to the elaborated scaffolds combined with molecular diversity and eco‐compatibility .…”