The role of home parenteral nutrition in the management of intestinal failure — report of 400 cases

O’Hanrahan, Tim; Irving, M. H.

doi:10.1016/0261-5614(92)90083-3

Cited by 66 publications

(22 citation statements)

References 21 publications

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“…This is partly explained by the increasing age of the long-term HPN patients represented in both surveys and by a change in the age profile, especially among patients with cancers. These findings resemble results from other centres in Europe [6,7] The average duration of HPN treatment was 5.4 years in the first survey and 5.1 years in this survey, partly due to the shorter HPN treatment periods in patients with cancers observed in the latest survey. IBD patients are generally long-term users of HPN (68 patients had an average of 2.8 catheter years) and cancer patients are short-term users (52 patients had an average of 1.4 catheter years).…”

Section: Discussionsupporting

confidence: 90%

Home parenteral nutrition in Denmark in the period from 1996 to 2001

Ugur

Marashdeh

Gottschalck

et al. 2006

Scandinavian Journal of Gastroenterology

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Section: Discussionsupporting

confidence: 90%

Home parenteral nutrition in Denmark in the period from 1996 to 2001

Ugur

Marashdeh

Gottschalck

et al. 2006

Scandinavian Journal of Gastroenterology

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“…Most cases of partial venous occlusion vanish after heparin and/or change of the line, whereas total occlusions usually persist for years (62). In some series central venous thrombosis has been associated with a mortality of about 20% (67,68), but in these series the incidences of thrombosis were very low: 0.06-0.07 per catheter year indicating that probably only the most severe cases were detected.…”

Section: Complicationsmentioning

confidence: 92%

“…An antibiotic lock approach seems successful in salvaging most catheters (66). With meticulous surveillance and treatment the mortality of catheter sepsis is low: <3% (62,67,68).…”

Section: Complicationsmentioning

confidence: 98%

Nutrition in Short-Bowel Syndrome

Ladefoged

Hessov

Jarnum

1996

Scandinavian Journal of Gastroenterology

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Ladefoged K, Hessov I, Jarnum S. Nutrition in short-bowel syndrome. Scand J Gastroenterol 1996;31 Short-bowel syndrome is a state of severe malabsorption secondary to extensive bowel resection. The most common reasons for extensive bowel resection are Crohn's disease and mesenteric infarction. The pathophysiological consequences depend on extent and site of resection, integrity and adaptation of the remaining bowel, and secondary effects on other organs. Most extensively bowel resected patients can be adequately nourished by mouth, especially since they develop compensatory hyperphagia. For patients with colon in function a high-carbohydrate low-fat diet is beneficial compared to a diet with a normal fat content, because it results in decreased diarrhoea, decreased faecal mineral losses, and increased energy assimilation. The relative amount of dietary fat does not influence stool mass or energy assimilation in jejunostomy patients. Patients with jejunostomy have a high faecal output of water, sodium, and divalent cations, and they often need permanent parenteral supply of saline as well as calcium and magnesium if their small intestinal remnant is <200 cm and parenteral nutritional support if they retain < 100 cm small bowel. In contrast, 50 cm of the jejunum often suffices for adequate oral nutrition if most of the colon is preserved. The majority of patients needing long-term intravenous supply are trained to administer parenteral nutrition at home (HPN). Most patients on HPN obtain a good or fair quality of life with hospital readmissions corresponding to an average of 10% of the HPN duration and an overall HPN related mortality of about 4%. (fax +45 5663 2101) SUPPI 216:122-31. Scand J Gastroenterol Downloaded from informahealthcare.com by Thomas Jefferson University on 12/26/14 For personal use only. Scand J Gastroenterol Downloaded from informahealthcare.com by Thomas Jefferson University on 12/26/14 For personal use only.

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“…The cost per year of life saved was in fact 24700, which is comparable with other wellaccepted technologies, such as renal replacement therapy. O'Hanrahan & Irving (1992) have also shown the high survival rate and good quality of life of patients undergoing parenteral nutrition at home for chronic gastrointestinal failure. Such studies form the basis for arguing the case with hospital managers for appointing a nutrition team as part of the overall strategy for nutritional care in the hospital.…”

Section: Parenteral Nutritionmentioning

confidence: 99%

The management of malnutrition in hospital

Allison¹

1996

Proc. Nutr. Soc.

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The role of home parenteral nutrition in the management of intestinal failure — report of 400 cases

Cited by 66 publications

References 21 publications

Home parenteral nutrition in Denmark in the period from 1996 to 2001

Home parenteral nutrition in Denmark in the period from 1996 to 2001

Nutrition in Short-Bowel Syndrome

The management of malnutrition in hospital

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