2016
DOI: 10.1155/2016/1098916
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The Role ofAnethum graveolensL. (Dill) in the Management of Diabetes

Abstract: Aim. There is evidence that Anethum graveolens (AG) has been used for centuries in Asian traditional medicine, and its constituents have useful effects on the control and management of diabetes and cardiovascular disorders. AG has many useful effects, including hypolipidemic and hypoglycemic effects, and it has been reported to reduce the incidence of diabetic complications. It acts mainly by affecting antioxidant capacity and change in some genes in glucose and lipid pathways. The aim of the present paper was… Show more

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Cited by 68 publications
(54 citation statements)
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“…The majority of VL compounds contain flavonoids in high concentration, which are the potent ROS scavengers. The hypolipidemic effect of some components of VL, like Valeriana oficinalis [24] and Anethum graveolensL [25] can also be involved in diminishment of blood ROS levels.…”
Section: Resultsmentioning
confidence: 99%
“…The majority of VL compounds contain flavonoids in high concentration, which are the potent ROS scavengers. The hypolipidemic effect of some components of VL, like Valeriana oficinalis [24] and Anethum graveolensL [25] can also be involved in diminishment of blood ROS levels.…”
Section: Resultsmentioning
confidence: 99%
“…On the other hand, pharmaceutical therapies such as insulin sensitizers, renin-angiotensin system blockers, lipid reducing drugs, vitamin E and natural antioxidants, have been used in clinical trials (7). For instance, herbal medicine and natural products can prevent or manage NAFLD or liver injury by various mechanisms, such as reducing liver lipid accumulation via reducing sterol regulatory element-binding protein 1c (SREBP-1c) expression, elevating β-fatty acid (FA) oxidation by increasing peroxisome proliferator activated receptor α (PPARα) expression, reducing IR, alleviating oxidative stress through increased antioxidant enzymes activity and suppressing inflammatory factors (8)(9)(10)(11)(12)(13)(14)(15). Although natural products or various vitamins and some chemical drugs are used in liver damage, recent therapies for NAFLD show few positive outcomes and some adverse effects.…”
Section: Treatment or Prevention Of Nafldmentioning
confidence: 99%
“…Hyperglycemia and oxidative stress are known as main factors in diabetic complications (2). In this respect, natural products which are capable of reducing blood glucose and scavenging of free radicals play major role in treatment of diabetes (3)(4)(5)(6).…”
Section: Introductionmentioning
confidence: 99%