The role of interstitial brachytherapy using template in locally advanced gynecological malignancies

Agrawal, Parimal; Singhal, Surinder K; Neema, J.P.; Suryanarayan, U; Vyas, Rakesh Kumar; Rathi, Akanksha; Bahadur, Anil Kumar

doi:10.1016/j.ygyno.2005.06.001

Cited by 22 publications

(6 citation statements)

References 12 publications

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“…3,6 The use of interstitial needles only, without placement of a central tandem despite the presence of a uterus, has been reported. 12 This may be due to institutional preference, difficulty dilating a stenotic cervical os due to tumor erosion, or absence of the cervix after external-beam RT. The myometrium has a very high tolerance for radiation.…”

mentioning

confidence: 99%

Increasing Brachytherapy Dose Predicts Survival for Interstitial and Tandem-Based Radiation for Stage IIIB Cervical Cancer

Viswanathan

Cormack

Rawal

et al. 2009

International Journal of Gynecological Cancer

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The dose to point A of approximately 85 Gy as associated with tandem use was a significant predictor of survival in patients with stage IIIB cervical carcinoma, indicating the significance of the central location of the high dose provided by the tandem. Patients selected for interstitial brachytherapy alone must receive sufficient dose, and a tandem should be placed whenever feasible for all patients with an intact uterus treated for locally advanced cervical cancer.

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mentioning

confidence: 99%

Increasing Brachytherapy Dose Predicts Survival for Interstitial and Tandem-Based Radiation for Stage IIIB Cervical Cancer

Viswanathan

Cormack

Rawal

et al. 2009

International Journal of Gynecological Cancer

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“…Interstitial radiotherapy by MUPIT is a good choice to deliver high‐dose radiation in recurrent gynecological malignancies after external beam radiotherapy where conventional brachytherapy application is not feasible and is likely to give optimal dose distribution. Furthermore, locoregional control obtained with ISRT is good and within the accepted range of complications 3–5 . This MUPIT template consists of a central large hole for placement of tandem and an array of small holes around this large hole for insertion of needles.…”

mentioning

confidence: 78%

“…Furthermore, locoregional control obtained with ISRT is good and within the accepted range of complications. [3][4][5] This MUPIT template consists of a central large hole for placement of tandem and an array of small holes around this large hole for insertion of needles. The eight needles were inserted into the tumor and surrounding tissue and withdrawn on the final day.…”

Section: Iatrogenic Vulvar Skin Metastases After Interstitial Radiothmentioning

confidence: 99%

Iatrogenic vulvar skin metastases after interstitial radiotherapy for recurrent cervical cancer

Yamashita

Okuma

Nakagawa

2009

The Journal of Dermatology

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“…Interstitial brachytherapy is indicated in the treatment of cervix cancer when the tumor extension cannot be adequately covered by intracavitary brachytherapy [1][2][3][4]. Sedation and pain management are required as interstitial brachytherapy is an inherently invasive, unpleasant, and painful procedure [5].…”

Section: Purposementioning

confidence: 99%

Non-anesthetist-administered moderate sedation with midazolam and fentanyl for outpatient MRI-aided hybrid intracavitary and interstitial brachytherapy in cervix cancer: a single-institution experience

Sommat¹,

Lin²,

Chew³

et al. 2021

jcb

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Purpose:The aim of the study was to determine the feasibility of interstitial brachytherapy under non-anesthetist-administered moderate sedation, to identify factors influencing the insertion, and the total procedural time.Material and methods: A total of 47 insertions with hybrid intracavitary and interstitial applicators were performed in 23 patients from March 2017 to March 2020. Moderate sedation was achieved with intravenous midazolam and fentanyl administered by non-anesthetist. Insertion time and procedural time was recorded. Univariate and multivariate analysis were performed to evaluate the impact of different factors on insertion and procedural time.Results: A total of 238 needles (range, 2-8 per insertion) were implanted, with an average insertion depth of 30 mm (range, 20-40 mm). The mean doses for midazolam and fentanyl were 3 mg (standard deviation [SD] = 1) and 53.3 mcg (SD = 23.9) per insertion, respectively. The median insertion time was 30 minutes (interquartile range [IQR] = 22-40), and the median total procedural time was 4.3 hours (IQR = 3.6-5.2). First time insertion, insertions performed before 2019, and higher midazolam dose were associated with significantly longer insertion time, whereas longer insertion time, MRIbased planning, and insertions performed before 2019 were associated with significantly longer total procedural time.Conclusions: Outpatient interstitial brachytherapy with non-anesthetist-administered sedation is achievable and well-tolerated. This method may significantly lessen the burden on hospital resources and has the potential to be cost-effective.

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The role of interstitial brachytherapy using template in locally advanced gynecological malignancies

Cited by 22 publications

References 12 publications

Increasing Brachytherapy Dose Predicts Survival for Interstitial and Tandem-Based Radiation for Stage IIIB Cervical Cancer

Increasing Brachytherapy Dose Predicts Survival for Interstitial and Tandem-Based Radiation for Stage IIIB Cervical Cancer

Iatrogenic vulvar skin metastases after interstitial radiotherapy for recurrent cervical cancer

Non-anesthetist-administered moderate sedation with midazolam and fentanyl for outpatient MRI-aided hybrid intracavitary and interstitial brachytherapy in cervix cancer: a single-institution experience

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