The Role of Invasive Monitoring in Traumatic Brain Injury

Carandang, Raphael A.

doi:10.1007/s40719-015-0022-y

Cited by 2 publications

(2 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Patients who have severe neurological dysfunction require the monitoring and management of multiple aspects of brain physiology including pressure, perfusion, oxygenation, cellular metabolism, and electrical activity. 4 In such cases, invasive monitoring can provide the real-time information of the brain during or after surgery to help obtain the best possible functional neurological outcome. 5 So far, there are few reports on the chemical probes that focus on miniaturizing the probe’s cross-sectional area for potential application in such surgery with small incision.…”

Section: Introductionmentioning

confidence: 99%

“…However, there are some vital signs that depend only on invasive monitoring. Patients who have severe neurological dysfunction require the monitoring and management of multiple aspects of brain physiology including pressure, perfusion, oxygenation, cellular metabolism, and electrical activity . In such cases, invasive monitoring can provide the real-time information of the brain during or after surgery to help obtain the best possible functional neurological outcome .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

A Cylindrical Ion Sensor Tip with a Diameter of 1.5 mm for Potentially Invasive Medical Application

Nguyen

Chen

et al. 2020

ACS Omega

View full text Add to dashboard Cite

A fine cylindrical chemical sensor tip is developed with optical fiber in the core, surrounded by a transparent cylinder of photopolymer Norland Optical Adhesive 61 (NOA 61), and covered by a polymer hydrogel mixed with sensing molecules. The overall diameter is as small as 1.5 mm. pH response is demonstrated using two approaches of sensing materials: (i) absorbing probe Phenol Red mixed with Rhodamine 6G fluorescent dye and (ii) 8-hydroxypyrene-1,3,6-trisulfonic acid fluorescent probe. Both the optical excitation and fluorescence signal collection are through the optical fibers. A time resolution of 10 s is achieved for pH variations. Good linearity is observed in the physiological range from pH 7.0 to pH 8.6 with reversible and reproducible outcomes. For in vitro urea measurement, the sensor tip can distinguish 1, 3, and 5 mM urea solution, which is a crucial range in saliva urea concentration. The miniaturized tip with such simple cylindrical symmetry is designed to detect vital signs during minimally invasive surgeries and can be potentially accompanied with endoscopes to enter human bodies.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

A Cylindrical Ion Sensor Tip with a Diameter of 1.5 mm for Potentially Invasive Medical Application

Nguyen

Chen

et al. 2020

ACS Omega

View full text Add to dashboard Cite

show abstract

The impact of brain tissue oxygenation monitoring on mortality in adult patients with severe traumatic brain injuries: a systematic review

Ennis

Avşar

Moore

et al. 2023

British Journal of Neuroscience Nursing

View full text Add to dashboard Cite

Background: Intracranial pressure (ICP) monitoring and cerebral perfusion pressure (CPP) monitoring are long established adjuncts in the management of traumatic brain injuries (TBIs). However, brain tissue oxygenation (PbtO2) monitoring, used in conjunction with ICP or CPP monitoring, is an additional element that could be used in directing the management of TBIs. Aims: To determine the impact of PbtO2 monitoring on mortality in adult patients with severe TBIs. Methods: A systematic review of electronic databases was performed in October 2021. A total of six articles were identified for inclusion. Data were extracted using a pre-designed extraction tool. Analysis was undertaken using RevMan for the mortality rates and a narrative analysis for the secondary outcomes. Findings: A total of 926 participants were evaluated. Of these, 269 received PbtO2 monitoring. There was no significant difference in mortality rates between the groups, with the PbtO2 and ICP/CPP groups having a mortality rate of 25% (72/284) and 26% (171/662), respectively. The odds ratio was calculated as 0.88 (0.63–1.23, P=0.45) suggesting a 37% reduction in the odds of mortality when PbtO2 is used. However, the 95% confidence intervals do indicate a non-statistical finding. Morbidity rates between the two groups were also similar, with some limited evidence (one study) demonstrating a higher fiscal cost associated with PbtO2 monitoring. Conclusions: There was no significant difference in mortality or morbidity rates between the two groups. Based on these results, this systematic review cannot support the addition of PbtO2 monitoring to guide the treatment of adult patients with severe TBIs.

show abstract

The Role of Invasive Monitoring in Traumatic Brain Injury

Cited by 2 publications

References 53 publications

A Cylindrical Ion Sensor Tip with a Diameter of 1.5 mm for Potentially Invasive Medical Application

A Cylindrical Ion Sensor Tip with a Diameter of 1.5 mm for Potentially Invasive Medical Application

The impact of brain tissue oxygenation monitoring on mortality in adult patients with severe traumatic brain injuries: a systematic review

Contact Info

Product

Resources

About