Based on structural equation modeling, this paper measures and evaluates the transformation of scientific and technological achievements of colleges and universities in terms of implicit and explicit variables. The PLS algorithm is used to measure the intrinsic factor, which is designed to follow the Gaussian distribution and reach the expected value through iterative loops. The indicators and parameters of the explicit variables are evaluated by combining the principal component analysis and the great likelihood method. According to the results, the factors that are influenced by the policy environment account for 16.5%, while the problem of capital investment accounts for 36.3%. The number of invention patents increased by 8.93% after measuring and assessing them using the method presented in this paper. It demonstrates that universities can explore their technological achievements in depth and enhance their scientific research level.