The Role of Laser Vascular Targeting and Retinoic Acid in Oral Cancer Inhibition

Abstract

The study demonstrated the greater advantage of combining pulsed-dye laser with retinoic acid over using either retinoic acid or pulsed-dye laser alone for delay of oral cancer progression. Clinical trials are warranted to establish efficacy in humans.

Letter to the Editor

“…[1][2][3][4][5][6][7][8][10][11][12][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] For several reasons the above assumption is not valid.…”

Laser-Assisted Low-Dose Retinoic Acid in Oral Cancer Chemoprevention

“…Tumor growth is dependent on angiogenesis for maintenance of an adequate blood supply 6 . Previous studies in our laboratory have demonstrated the effectiveness of the antiangiogenesis agent, retinoic acid (RA), in the chemoprevention of HNSCC 7,8 . It has a high incidence of side effects, however, which include dry skin, cheilitis, conjunctivitis, and hypertriglyceridemia 5 …”