2014
DOI: 10.1177/0268355514528128
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The Role of Leg Compression in the Treatment of Deep Vein Thrombosis

Abstract: Up until today mobile outpatients are put into bed as soon as the diagnosis of deep vein thrombosis (DVT) is made. Fear of pulmonary embolism (PE) is the main rationale for bed-rest; additional arguments are pain and swelling which are expected to resolve faster during leg elevation. Based on previous work it is demonstrated that keeping mobile patients with acute DVT walking under exact anticoagulation does not increase the risk for symptomatic PE in comparison with bed-rest and that there is an immediate red… Show more

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Cited by 14 publications
(11 citation statements)
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“…2,7) Venous sheath placement itself might promote thrombogenesis by injuring the vessel wall, reducing the lumen and activating the coagulation cascade, 8) which of action is the increase of shear stress in microcirculation of the vein wall releasing anti-inflammatory and anti-coagulatory mediators. 10) Although compression therapies are costly, cumbersome to use, and can cause skin injury, they should be recommended as prophylaxis especially in patients with high risk of VTE. Generally, immediate contrast-enhanced CT scan is employed as the imaging modality of first choice to assess the severity of pulmonary thromboembolism.…”
Section: Discussionmentioning
confidence: 99%
“…2,7) Venous sheath placement itself might promote thrombogenesis by injuring the vessel wall, reducing the lumen and activating the coagulation cascade, 8) which of action is the increase of shear stress in microcirculation of the vein wall releasing anti-inflammatory and anti-coagulatory mediators. 10) Although compression therapies are costly, cumbersome to use, and can cause skin injury, they should be recommended as prophylaxis especially in patients with high risk of VTE. Generally, immediate contrast-enhanced CT scan is employed as the imaging modality of first choice to assess the severity of pulmonary thromboembolism.…”
Section: Discussionmentioning
confidence: 99%
“…Es zeigte sich eine positive Korrelation zwischen der Ejektionsfraktion und den Druckspitzen an der Wade, nicht aber in der Knöchelregion [13]. [22,23]. Für die Kompressionstherapie wird eine Dauer von 2 Jahren empfohlen.…”
Section: Kompressionstherapie Als Prophylaxe Beim Postoperativen Bypaunclassified
“…Für die Kompressionstherapie wird eine Dauer von 2 Jahren empfohlen. Wann immer möglich, sollten diese Patienten mobil bleiben und zu regelmäßigem Gehen in der Kompression angehalten werden [22]. Die Bewegung in der Kompression trägt dazu bei, den Venendurchmesser zu reduzieren, den venösen Abstrom zu erhöhen und die Scherkraftinduzierte Plättchenaktivierung und Entzündungsaktivität an der Venenwand zu reduzieren [22,24].…”
Section: Kompressionstherapie Als Prophylaxe Beim Postoperativen Bypaunclassified
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“…Regarding proper management, research data indicate that immediate compression and early walking also reduces the incidence of PTS [16]. One presumed mechanism of action of this adjunct treatment modality is the increase of shear stress in the microcirculation of the vein wall releasing anti-inflammatory and anti-coagulatory mediators [17]. Daily use of elastic compression stockings for 2 years after proximal DVT appears to reduce the risk as well [14]; however, there is uncertainty about optimal duration of use and compression strength of elastic stockings and the magnitude of their effect.…”
mentioning
confidence: 99%