The role of leukotrienes in acute hypoxic pulmonary vasoconstriction in rats

Li, S.; Wang, D X

doi:10.1007/bf02909750

Cited by 2 publications

(1 citation statement)

References 15 publications

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“…The sag curve of inclined cable use the second parabolic form according to the literature [10] ,which takes into account the influence of the tension variety along the inclined cable, the form is…”

Section: The Nonlinear Vibration Equation Of Inclined Cablementioning

confidence: 99%

Influence of the Tension Variety on Non-Linear Natural Frequency of an Inclined Cable

Liu

2010

AMR

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According to the vibration characteristics of small sag cable, an equation of non-linear free transverse in-plane vibration of an inclined cable is presented considering the effects of the flexural rigidity. In the equation the influence of the tension variety along the inclined cable was taken into account by using the precise parabola equation of the taut cable. Taking single mode of a cable in consideration, the governing equation was simplified as a traditional Duffing equation with a quadratic term. It was solved by using the method of Fourier series. Combined with engineering practice, an example was provided to study nonlinear natural vibration characteristic of an inclined cable in plane when the length, the inclination angle, the tension were changed separately, whether considering the influence of tension variety along the inclined cable or not.

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Section: The Nonlinear Vibration Equation Of Inclined Cablementioning

confidence: 99%

Influence of the Tension Variety on Non-Linear Natural Frequency of an Inclined Cable

Liu

2010

AMR

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Effects of cigarette smoking on hemodynamics and hypoxic pulmonary vasoconstriction: Role of prostaglandins and leukotrienes

Chen¹,

Dx²

1989

Journal of Tongji Medical University

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This study investigated the role of prostaglandins (PGs) and leukotrieres (LTs) in hypoxic pulmonary vasoconstriction (HPV) and in cigarette smoking-induced changes in hemodynamics and HPV in Wistar rats. Selective LTD4-LTE4 receptor antagonist LY-171883 (LY) inhibited HPV by 71.8%, while cyclooxygenase inhibitor indomethacin (IND) augmented HPV. The results indicate that LTs mediate HPV in Wistar rats. Smoking increased the level of TXB2 over control by 143.6% in plasma and 69.2% in lung tissue, concomitantly, pulmonary and systemic vascular resistance (PVR and SVR) were increased by 38.7% and 46.7%, respectively. Both LY and IND prevented the smoking-induced increase of PVR and SVR. After smoking HPV increased twofold. The increase of HPV was abolished by LY, but not by IND. Our results suggest that smoking leads to pulmonary and systemic vasoconstriction partly mediated by TXA2 and LTs; smoking also leads to an augmentation of HPV, and LTs play an important role in it.

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The role of leukotrienes in acute hypoxic pulmonary vasoconstriction in rats

Cited by 2 publications

References 15 publications

Influence of the Tension Variety on Non-Linear Natural Frequency of an Inclined Cable

Influence of the Tension Variety on Non-Linear Natural Frequency of an Inclined Cable

Effects of cigarette smoking on hemodynamics and hypoxic pulmonary vasoconstriction: Role of prostaglandins and leukotrienes

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