The Role of Low-Density Lipoprotein Receptor-Associated Protein LRP11 in the Development of Hepatocellular Carcinoma
Jinxian Pei,
Huihui Wang,
Yan Zhang
et al.
Abstract:This study investigated the role of the low-density lipoprotein receptor-associated protein LRP11 in hepatocellular carcinoma (HCC). Analysis of TCGA and GTEx databases revealed that LRP11 expression was significantly increased in liver cancer tissues compared to normal tissues (P
<0.05). High expression of LRP11 was associated with shorter survival in liver cancer patients (P <0.05). Lentivirus transfection was used to create sh-NC and sh-LRP11 groups for further experiments. Silencing LRP11 in HepG2 c… Show more
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