2017
DOI: 10.1016/j.jtemb.2017.05.009
|View full text |Cite
|
Sign up to set email alerts
|

The role of lysosomes in the phenomenon of concentration of aluminum and indium in the female reproductive system. An ultrastructural study

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

2
5
0

Year Published

2018
2018
2024
2024

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 10 publications
(7 citation statements)
references
References 17 publications
2
5
0
Order By: Relevance
“…Reduced ingestion rate in Daphnia after cadmium exposure was suggested to be a key mechanism impairing energy uptake and thus reproduction and growth . Despite potentially reduced ingestion rate, the highest concentrations of Al and In were detected in the midgut, which is in line with other studies on metal uptake in D. magna . Al crossing cell membranes by endocytosis are found accumulated in lysosomes. , The lysosome cellular component (Table S3) was enriched in all the treatment groups and endocytosis in the mixture, suggesting their involvement in Al and In accumulation and effects.…”
Section: Discussionsupporting
confidence: 85%
See 1 more Smart Citation
“…Reduced ingestion rate in Daphnia after cadmium exposure was suggested to be a key mechanism impairing energy uptake and thus reproduction and growth . Despite potentially reduced ingestion rate, the highest concentrations of Al and In were detected in the midgut, which is in line with other studies on metal uptake in D. magna . Al crossing cell membranes by endocytosis are found accumulated in lysosomes. , The lysosome cellular component (Table S3) was enriched in all the treatment groups and endocytosis in the mixture, suggesting their involvement in Al and In accumulation and effects.…”
Section: Discussionsupporting
confidence: 85%
“…52 Al crossing cell membranes by endocytosis are found accumulated in lysosomes. 52,53 The lysosome cellular component (Table S3, SI) was enriched in all the treatment groups and endocytosis in the mixture, suggesting their involvement 21…”
mentioning
confidence: 99%
“…Our ultrastructural results reminder many previous studies describing that cerium, a mineral element which belonging to the same group of lanthanum, was found within the lysosomes of intestinal mucosa, liver, kidney, suprarenal, and testicular glands cells [14] as well as endometrium and myometrium cells, granulosa and internal theca cells of the ovary [15]. In addition, our observed deposits were similar to those founded with gadolinium in alveolar macrophages [17,10], liver cells, spleen, bone marrow, proximal renal cells [20], endometrium, myometrium, granulosa and internal theca cells [13]. Indeed, the same processes of precipitation within the lysosomes were highlighted with heavy metals.…”
Section: Discussionsupporting
confidence: 73%
“…For example, the III A group of the Mendeleev chart, such as gallium, which deposits were identified in the lysosomes of tumoral cells [6], and aluminum selectively concentrated in the lysosomes of bone marrow, liver, and mammary gland cells [7][8][9]. As for rare earths, gadolinium was found in several kinds of cells such as alveolar macrophages, liver cells [10][11][12], endometrium, myometrium, granulosa and internal theca cells [13]. An intralysosomal detection of cerium was mentionnated in the intestinal mucosa, liver, kidney, suprarenal, and testicular glands [14].…”
Section: Discussionmentioning
confidence: 99%
“…A study published in the J Trace Elem Med Bio highlighted fine ultrastructural details of cellular components from myometrial and endometrium cells, and in the cells of the ovary (internal theca and granulosa cells). Lysosomes were extracted, and the analysis compared with other tissues shows crystallized fragments inside the lysosomes as part of their cellular role by phagocytosing aluminum ready for disposal [ 238 ]. Here a suggestion was made to assess endocrine function and female fertility with aluminum exposure.…”
Section: Trace Elements and Female Reproductive Organsmentioning
confidence: 99%