The Role of Magnetic Resonance Imaging in the Early Diagnosis of Rheumatoid Arthritis

Ashikyan, Oganes; Tehranzadeh, Jamshid

doi:10.1097/rmr.0b013e318093f59b

Cited by 11 publications

(9 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Bei negativen oder niedrigeren (< 50 U/ml) Werten ist die Bestimmung von Antikörpern gegen cyclische citrullinier- [10] . Jedoch zeigen serielle Untersuchungen, dass nur rund 25% der im MRT sichtbaren Erosionen auch in weiterer Folge nativradiologisch auftreten [11,12] .…”

Section: Labor-analysenunclassified

Rheumatoide Arthritis

Stummvoll

Nöbauer-Huhmann

Machold

et al. 2008

Wiener Klin. Wochenschr. Educ.

View full text Add to dashboard Cite

Section: Labor-analysenunclassified

Rheumatoide Arthritis

Stummvoll

Nöbauer-Huhmann

Machold

et al. 2008

Wiener Klin. Wochenschr. Educ.

View full text Add to dashboard Cite

“…Wrist, metacarpophalangeal and metatarsophalangeal joints are the first sites to be affected. [1][2][3][4][5][6][7][8][9][10] According to the epidemiological data, RA affects 1% of the population. While it shows a slow progression in some patients, in some it has a course characterized by rapid destruction of the bone and joint space.…”

mentioning

confidence: 99%

“…Initial symptoms are observed in people between the ages of 40-60 years old. [4] Diagnosis is established by clinical, laboratory, and radiological findings. As a result of advanced treatment methods, early diagnosis bears importance in preventing arthritis from progression to advanced stages.…”

mentioning

confidence: 99%

“…[13] Since then, a large number of publications using MRI in RA have demonstrated its usefulness in the detection of early period inflammatory and structural changes in RA cases. [1][2][3][4][5][6][7][8][9][10][11][12]14,15] Moreover, MRI is the ideal instrument for the evaluation of treatment response. [16] Since 1998, an international Outcome Measures in Rheumatology Clinical Trials (OMERACT) MRI in an RA working group has aimed to develop MRI scoring systems to assess RA inflammation (activity) and damage which would satisfy the elements of the OMERACT filter (truth, discrimination, and feasibility).…”

mentioning

confidence: 99%

See 1 more Smart Citation

Importance of MRI in Showing the Early Period Erosive Alterations During Wrist Involvement in Rheumatoid Arthritis

Gökalp

Yazıcı

2011

Turk J Rheumatol

View full text Add to dashboard Cite

Amaç: Bu çalışmada, romatoid artritin (RA) erken dönem eroziv değişikliklerinin ortaya konmasında, manyetik resonans görüntülemenin (MRG) etkinliği değerlendirildi. Hastalar ve yöntemler:Klinik veriler ve laboratuvar sonuçlarıyla RA tanısı konulan 14 hastada (11 kadın, 3 erkek; ort yaş 54 yıl; dağılım 37-64 yıl) 21 el bileği MRG ile incelendi. Hastalık aktivitesi C-reaktif protein ve eritrosit sedimantasyon oranı ile belirlendi. Hastaların hepsinde el bileği grafisi normaldi ya da şüpheli bulgular vardı. Kemik erozyonlarının varlığı 15 farklı bölgede (8 karpal kemik, 5 metakarp başı, 1 distal radius ve 1 distal ulna) değerlendirildi. Yağ baskılamalı ve yağ baskılamasız koronal ve aksiyal T1-ağırlıklı spin eko (SE) görüntüleri, yağ baskılamalı T2-ağırlıklı koronal turbo SE görüntüleri ve intravenöz gadopentetat dimeglumin verilmesinden sonra yağ baskılamalı T1-ağırlıklı koronal SE görüntüleri elde edildi. Bulgular:Olguların hepsinde el bileği grafisi ya normaldi ya da şüpheli bulgular vardı. Karpal kemiklerde 73 (%81.1) farklı bölgede, distal radiusta dört (%4.4) farklı bölgede, distal ulnada dört (%4.4) farklı bölgede, proximal metakarp başlarında dokuz (%10) farklı bölgede kemik erozyonu tespit edildi. Kapitatum (%27.3) ve triquetrum (%24.6) en çok ekilenen bölge iken, pisiforme en az etkilenen bölge (%1.6) olarak tespit edildi. Erozyon saptanan 21 elbileği MRG'sinin dokuzunda (%42.8) sinovit, üçünde tenosinovit (%14.2), ikisinde bursit (%9.5) ve yedisinde kemik iliği ödemi (%33.3) vardı.Sonuç: Manyetik resonans görüntüleme RA'lı olgularda erken dönem eklem tutulumunu saptamada etkin bir tanı yöntemi olabilir.Anahtar sözcükler: Erozyon; manyetik rezonans görüntüleme; romatoid artrit. Objectives:In this study, we aimed to evaluate the efficacy of magnetic resonance imaging (MRI) in demonstrating erosive alterations during the early period of rheumatoid arthritis (RA). Patients and methods:Twenty-one wrists of 14 patients (11 females, 3 males; mean age 54 years; range 37 to 64 years) diagnosed with RA by clinical data and laboratory results were examined with MRI. The disease activity was determined by C-reactive protein and erythrocyte sedimentation rates. Wrist radiographies of all the patients were either normal or had suspicious signs. The presence of bone erosion was evaluated in 15 different regions (8 carpal bones, 5 metacarpal heads, 1 distal radius, and 1 distal ulna). Coronal and axial T1-weighted spin echo (SE) images with and without fat suppression, coronal T2-weighted turbo SE images with fat suppression, and coronal T1-weighted SE images with fat suppression following administration of intravenous gadopenteate dimeglumine were obtained. Results:In all cases, the wrist radiographs were either normal or exhibited suspicious findings. Bone erosion was found in 73 (81.1%) different sites in carpal bones, four different sites in distal radius (4.4%), four (4.4%) different sites in distal ulna, and nine (10%) different sites in proximal metacarpal heads. While capitatum (27.3%) and triquetrum (24.6%) wer...

show abstract

“…[10,11]. Auch mittels MagnetresonanzTomographie (MRT) können insbesondere nach Verabreichung von Kontrastmittel (Gaddinium) Entzündungen besser zur Darstellung gebracht werden [12,13] (Abb. 5).…”

unclassified

Arthritis – rechtzeitig handeln heißt behandeln

Köller

Nöbauer-Huhmann

2009

Wien Med Wochenschr

View full text Add to dashboard Cite

Rheumatoid Arthritis (RA) is the most prevalent inflammatory joint disease in adults and shows a destructive course in most cases. The outcome of the disease - functional decline and invalidity - necessitates an early therapy. Recent studies demonstrate that the initiation of the treatment with a disease modifying antirheumatic drug (DMARD) treatment within the first three months after the onset of symptoms is crucial for sustained improvement of prognosis as well as therapeutic success and outcome. In the early stage of the disease, the criteria for the classification of Rheumatoid Arthritis (RA) are frequently not met. Up to over 50% of the patients show an arthritis, which cannot be classified and therefore is seen as undifferentiated arthritis (UA). Early therapeutic intervention appears to prevent the chronification of the disease; thus an early and appropriate disease modifying therapy is mandatory. Age, gender, involvement of the hands, positive rheumatoid factor, as well as the detection of anti cyclic-citrullinated peptide antibodies (anti-CCP Ab) are predictors of the development of RA. Beside conventional X-rays, there are other imaging methods such as magnetic resonance tomography imaging, Power-Doppler or contrast medium enhanced sonography, which may enable the detection not only of synovitis but also of erosive lesions at very early stages. Those patients suffering from UA carry a high risk for the development of a destructive arthritis as seen in RA, and therefore should be treated with an adequate DMARD. In these cases methotrexate is still the drug of first choice.

show abstract

The Role of Magnetic Resonance Imaging in the Early Diagnosis of Rheumatoid Arthritis

Cited by 11 publications

References 42 publications

Rheumatoide Arthritis

Rheumatoide Arthritis

Importance of MRI in Showing the Early Period Erosive Alterations During Wrist Involvement in Rheumatoid Arthritis

Arthritis – rechtzeitig handeln heißt behandeln

Contact Info

Product

Resources

About