The role of MRI in the evaluation of muscle diseases

El-Essawy, Saleh; Borg, Mohamed A; Mohamed, Mohamed Abd El-Salam; Elhawary, Galal; El-Salam, Eman Mohamed Abd

doi:10.1016/j.ejrnm.2013.04.002

Cited by 6 publications

(4 citation statements)

References 11 publications

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“…Magnetic resonance imaging (MRI) has been used to assess skeletal muscle morphology and composition for over four decades [ 1 – 3 ]. Assessment of skeletal muscle with MRI can contribute to improved understanding of normal responses to physical activity and changes associated with healthy ageing, muscle injury, and pathology [ 1 , 4 ]. Advancing MRI technologies, including a range of faster, higher resolution techniques continue to emerge with the aim of improving visualisation and quantification of muscle characteristics [ 5 – 7 ].…”

Section: Introductionmentioning

confidence: 99%

Towards defining muscular regions of interest from axial magnetic resonance imaging with anatomical cross-reference: a scoping review of lateral hip musculature

Perraton

Lawrenson

Mosler

et al. 2022

BMC Musculoskelet Disord

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Background Measures of hip muscle morphology and composition (e.g., muscle size and fatty infiltration) are possible with magnetic resonance imaging (MRI). Standardised protocols or guidelines do not exist for evaluation of hip muscle characteristics, hindering reliable and valid inter-study analysis. This scoping review aimed to collate and synthesise MRI methods for measuring lateral hip muscle size and fatty infiltration to inform the future development of standardised protocols. Methods Five electronic databases (Medline, CINAHL, Embase, SportsDISCUS and AMED) were searched. Healthy or musculoskeletal pain populations that used MRI to assess lateral hip muscle size and fatty infiltration were included. Lateral hip muscles of interest included tensor fascia late (TFL), gluteus maximus, gluteus medius, and gluteus minimus. Data on MRI parameters, axial slice location, muscle size and fatty infiltrate measures were collected and analysed. Cross referencing for anatomical locations were made between MRI axial slice and E-12 anatomical plastinate sections. Results From 2684 identified publications, 78 studies contributed data on volume (n = 31), cross sectional area (CSA) (n = 24), and fatty infiltration (n = 40). Heterogeneity was observed for MRI parameters and anatomical boundaries scrutinizing hip muscle size and fatty infiltration. Seven single level axial slices were identified that provided consistent CSA measurement, including three for both gluteus maximus and TFL, and four for both gluteus medius and minimus. For assessment of fatty infiltration, six axial slice locations were identified including two for TFL, and four for each of the gluteal muscles. Conclusions Several consistent anatomical levels were identified for single axial MR slice to facilitate muscle size and fatty infiltration muscle measures at the hip, providing the basis for reliable and accurate data synthesis and improvements in the validity of future between studies analyses. This work establishes the platform for standardised methods for the MRI assessment of lateral hip musculature and will aid in the examination of musculoskeletal conditions around the hip joint. Further studies into whole muscle measures are required to further optimise methodological parameters for hip muscle assessment.

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Section: Introductionmentioning

confidence: 99%

Towards defining muscular regions of interest from axial magnetic resonance imaging with anatomical cross-reference: a scoping review of lateral hip musculature

Perraton

Lawrenson

Mosler

et al. 2022

BMC Musculoskelet Disord

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“…Because quantitative evaluation systems are based on computer analysis of the pixel intensity values, they provide a more precise evaluation of the muscle changes with statistically well-defined outcomes. These quantitative methods showed a good correlation with semi-quantitative evaluation systems [74,75].…”

Section: ) Clinical Applications Of Mri In Rheumatic Diseasesmentioning

confidence: 75%

Utility of Magnetic Resonance Imaging and Positron Emission Tomography in Rheumatic Diseases

2020

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The use of magnetic resonance imaging (MRI) and positron emission tomography (PET) in rheumatology allows a better understanding of the pathophysiology of the disease as well as early diagnosis and appropriate evaluation of the disease status and treatment responses. Despite the limited availability because of the high cost, there is growing evidence for the advantages and clinical application of these modalities to various rheumatic diseases. This review discusses the basic mechanisms and clinical applications of MRI and PET in certain rheumatic diseases, including rheumatoid arthritis, axial spondyloarthritis, idiopathic inflammatory myopathies, large vessel vasculitis, central nervous system disease associated with rheumatic diseases, polymyalgia rheumatica, adult-onset Still's disease, and immunoglobulin G4-related disease.

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“…imaging techniques) is commonly employed to evaluate symmetry, extent of disease, and response to therapy. A number of novel MR imaging techniques have been employed for the evaluation of muscle disorders, including perfusion and oxygenation mapping; diffusion techniques, including tractography to assess architecture; T2 mapping for quantitative measurement of tissue fluid and fat; MR elastography to evaluate tissue compliance and interstitial fibrosis; and phosphorus ( 31 P) MR spectroscopy to evaluate muscle composition and energetics (3)(4)(5)(6)(7).…”

Section: Introductionmentioning

confidence: 99%

MR Imaging of Atraumatic Muscle Disorders

et al. 2018

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Atraumatic disorders of skeletal muscles include congenital variants; inherited myopathies; acquired inflammatory, infectious, or ischemic disorders; neoplastic diseases; and conditions leading to muscle atrophy. These have overlapping appearances at magnetic resonance (MR) imaging and are challenging for the radiologist to differentiate. The authors organize muscle disorders into four MR imaging patterns: (a) abnormal anatomy with normal signal intensity, (b) edema/inflammation, (c) mass, and (d) atrophy, highlighting each of their key clinical and imaging findings. Anatomic muscle variants, while common, do not produce signal intensity alterations and therefore are easily overlooked. Muscle edema is the most common pattern but is nonspecific, with a broad differential diagnosis. Autoimmune, paraneoplastic, and drug-induced myositis tend to be symmetric, whereas infection, radiation-induced injury, and myonecrosis are focal asymmetric processes. Architectural distortion in the setting of muscle edema suggests one of these latter processes. Intramuscular masses include primary neoplasms, metastases, and several benign masslike lesions that simulate malignancy. Some lesions, such as lipomas, low-flow vascular malformations, fibromatoses, and subacute hematomas, are distinctive, but many intramuscular masses ultimately require a biopsy for definitive diagnosis. Atrophy is the irreversible end result of any muscle disease of sufficient severity and is the dominant finding in disorders such as the muscular dystrophies, denervation myopathy, and sarcopenia. This imaging-based classification, in correlation with clinical and laboratory data, will aid the radiologist in interpreting MR imaging findings in patients with atraumatic muscle disorders. RSNA, 2018.

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The role of MRI in the evaluation of muscle diseases

Cited by 6 publications

References 11 publications

Towards defining muscular regions of interest from axial magnetic resonance imaging with anatomical cross-reference: a scoping review of lateral hip musculature

Towards defining muscular regions of interest from axial magnetic resonance imaging with anatomical cross-reference: a scoping review of lateral hip musculature

Utility of Magnetic Resonance Imaging and Positron Emission Tomography in Rheumatic Diseases

MR Imaging of Atraumatic Muscle Disorders

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