The Role of MRI-TRUS Fusion Biopsy in the Diagnosis of Clinical Significant Prostate Cancer (CsPca)

Abstract

Despite its limitations, ultrasound-guided biopsy is still the "gold standard" for the diagnosis of prostate cancer (PCa). Multiparametric magnetic resonance imaging (mp-MRI) plays an increasingly important role in patients with prior negative biopsy; several studies report an improved clinically significant prostate cancer (Cs PCa) detection rate for MRI-targeted biopsy compared to the standard biopsy. There are currently three techniques for the MRI-targeted biopsy: the cognitive registration, the software-assisted fusion registration, and the in-bore biopsy. The best MRI-targeted biopsy technique is still a matter of debate in literature; however, MRI/TRUS fusion-guided biopsy is often described as the most accurate and cost-effective approach; we describe the technique and its results.