The role of neurophysiological methods in the confirmation of brain death

Djuric, Stojanka; Đurić, Vanja; Milošević, Vuk; Stamenović, Jelena; Mihaljev-Martinov, J

doi:10.2298/vsp110224046d

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…As opposed to the studies above that rely on visualization of blood flow, EEG has the ability to detect electrical activity, and as one of the first neurologic tests in general, it has long been used to augment the clinical determination of BD/DNC [ 85 , 86 ]. However, EEG has perhaps proved more valuable in cases that aim to detect subtle meaningful residual cerebral activity, such as covert consciousness, rather than to exclude the presence of meaningful cerebral function [ 16 , 18 , 19 , 87 ].…”

Section: Ancillary Testingmentioning

confidence: 99%

“…As such, EEG is not recommended as an ancillary test in adults unless otherwise required by local laws or protocols. In the evaluation of BD/DNC, EEG is limited by its ability to detect only cortical activity reliably [ 86 , 88 ], and lack of ability to assess the posterior fossa/brainstem. In general, and particularly in an ICU setting, interpretation is limited by a number of artifacts, leading to potential false negatives, and EEG activity may be artificially suppressed in a number of clinical scenarios including TTM or sedation, leading to false positives [ 86 , 88 , 89 ].…”

Section: Ancillary Testingmentioning

confidence: 99%

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Brain death: a clinical overview

2022

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Brain death, also commonly referred to as death by neurologic criteria, has been considered a legal definition of death for decades. Its determination involves many considerations and subtleties. In this review, we discuss the philosophy and history of brain death, its clinical determination, and special considerations. We discuss performance of the main clinical components of the brain death exam: assessment of coma, cranial nerves, motor testing, and apnea testing. We also discuss common ancillary tests, including advantages and pitfalls. Special discussion is given to extracorporeal membrane oxygenation, target temperature management, and determination of brain death in pediatric populations. Lastly, we discuss existing controversies and future directions in the field.

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Section: Ancillary Testingmentioning

confidence: 99%

Section: Ancillary Testingmentioning

confidence: 99%

Brain death: a clinical overview

2022

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Diagnosing Brain Death

Ramachandran

2024

Principles and Practice of Neurocritical Care

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Management of Potential Organ Donor: Indian Society of Critical Care Medicine—Position Statement

Mani,

Karanth,

Prabhakar

et al. 2024

Indian Journal of Critical Care Medicine

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A bstract This position statement is documented based on the input from all contributing coauthors from the Indian Society of Critical Care Medicine (ISCCM), following a comprehensive literature review and summary of current scientific evidence. Its objective is to provide the standard perspective for the management of potential organ/tissue donors after brain death (BD) in adults only, regardless of the availability of technology. This document should only be used for guidance only and is not a substitute for proper clinical decision making in particular circumstances of any case. Endorsement by the ISCCM does not imply that the statements given in the document are applicable in all or in a particular case; however, they may provide guidance for the users thus facilitating maximum organ availability from brain-dead patients. Thus, the care of potential brain-dead organ donors is “caring for multiple recipients.” How to cite this article Zirpe K, Pandit R, Gurav S, Mani RK, Prabhakar H, Clerk A, et al . Management of Potential Organ Donor: Indian Society of Critical Care Medicine—Position Statement. Indian J Crit Care Med 2024;28(S2):S249–278.

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The role of neurophysiological methods in the confirmation of brain death

Abstract: nem

Cited by 3 publications

References 17 publications

Brain death: a clinical overview

Brain death: a clinical overview

Diagnosing Brain Death

Management of Potential Organ Donor: Indian Society of Critical Care Medicine—Position Statement

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