The Role of Nutrition in Chronic Disease

Gropper, Sareen S.

doi:10.3390/nu15030664

Cited by 49 publications

(20 citation statements)

References 15 publications

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“…The promising results we have, although failing to show a significant difference compared to control, suggest a possible role of the combined MPE + CRE in selectively increasing HDL-C, with their known anti-atherogenic effects. This was in good agreement with the previous works of Qin et al [1] and Labban et al [41], in which there were anti-dyslipidemia effects of CRE, MPE, and the combination of both. It was hopeful to report that CRE could be protective in individuals at risk of CVD through improving serum lipid levels and may be used as a safe dietary supplement with conventional drugs [1].…”

Section: Discussionsupporting

confidence: 93%

“…This was in good agreement with the previous works of Qin et al [1] and Labban et al [41], in which there were anti-dyslipidemia effects of CRE, MPE, and the combination of both. It was hopeful to report that CRE could be protective in individuals at risk of CVD through improving serum lipid levels and may be used as a safe dietary supplement with conventional drugs [1].…”

Section: Discussionsupporting

confidence: 93%

“…Numerous chronic disorders, such as obesity, cardiovascular disease, hypertension, stroke, type 2 diabetes, metabolic syndrome, several malignancies, and possibly some neurological diseases, are influenced by diet, which is frequently viewed as a lifestyle component. Plants are the primary source of natural medications utilized in traditional therapeutic modalities [1].…”

Section: Introductionmentioning

confidence: 99%

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Biological Properties in Relation to the Health-Promoting Effects of Independent and Combined Garcinia mangostana Pericarp and Curcuma in Lean Wistar Albino Rats

et al. 2023

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With the increase in verifications and proofs highlighting the association between diet and health, several food products, such as phenolic rich fruits and vegetables, have emerged as possessing potential health benefits. Plants rich with fiber and phenolic content have long been considered as a health-promoting dietary intervention. Therefore, the present work aimed to test the independent and combined potential benefits of mangosteen pericarp extract (MPE) and curcuma rhizome extract (CRE) consumption through an in vivo study on Wister albino rats. The data demonstrated that the three nutritional interventions had no effect on serotonin or glutamate, but dopamine was considerably increased in response to the combined effects of MPE and curcuma (p ˂ 0.025). The anti-inflammatory potency of independent MPE and curcuma, as well as their combined effects, recorded lower levels of IL12 in all groups compared to controls (p ˂ 0.05), and only a considerably lower IL-6 in combination treatment only (p ˂ 0.028). The three dietary interventions dramatically lowered leptin levels, with the combined treatment significantly lower than the healthy control group (p ˂ 0.001). The combined treatment significantly improved levels of malondialdehyde (MDA) and GSH as indicators of oxidative stress and antioxidant capability. Our data reported anti-dyslipidemic and anti-hyperglycemic effects of the three studied nutritional interventions, with the independent curcuma being the most effective anti-hyperglycemic compound (p ˂ 0.009). Collectively, the three used nutritional intervention strategies demonstrated promising health-promoting effects with no side effects.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

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Biological Properties in Relation to the Health-Promoting Effects of Independent and Combined Garcinia mangostana Pericarp and Curcuma in Lean Wistar Albino Rats

et al. 2023

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“…43 Similar interventions may be beneficial for older PwH who are overweight or obese. Lastly, exercise and healthy nutrition have the potential to improve multiple health outcomes and chronic health issues simultaneously, 44,45…”

Section: Optimisation Of Pain Management and Physical Function In Old...mentioning

confidence: 99%

“…Similar interventions may be beneficial for older PwH who are overweight or obese. Lastly, exercise and healthy nutrition have the potential to improve multiple health outcomes and chronic health issues simultaneously, 44,45 offering the potential to benefit additional comorbidities other than pain alone amongst older PwH living with multimorbidity, including cardiovascular disease, type 2 diabetes, and human immunodeficiency virus.…”

Section: Optimisation Of Pain Management and Physical Function In Old...mentioning

confidence: 99%

Challenges in ageing persons with haemophilia

Makris,

Lassila,

Kennedy

2024

Haemophilia

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As treatments for individuals with inherited bleeding disorders improve, life expectancy increases and is approaching that of the normal population. Concomitant with this we are now seeing the problems of ageing in the bleeding disorder population. Although the clear‐cut association between low clotting factor levels and risk of bleeding is well recognised, a relationship between high levels, some non‐factor therapies and thrombotic risk also exists. The management of thrombosis in persons with inherited bleeding disorders is complex but manageable with modern treatments and collaboration in decision making between health care professionals and patients. Despite the improvements in treatment and reduction in bleeding, mostly musculoskeletal pain continues to be a major issue with advancing age. The management of pain amongst older people with haemophilia who may have multiple comorbidities should involve a person‐centred, holistic, multi‐disciplinary approach to support and optimise long‐term physical functioning and overall quality of life.

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Proposed Nutrition Competencies for Medical Students and Physician Trainees

Eisenberg,

Cole,

Maile

et al. 2024

JAMA Netw Open

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ImportanceIn 2022, the US House of Representatives passed a bipartisan resolution (House of Representatives Resolution 1118 at the 117th Congress [2021-2022]) calling for meaningful nutrition education for medical trainees. This was prompted by increasing health care spending attributed to the growing prevalence of nutrition-related diseases and the substantial federal funding via Medicare that supports graduate medical education. In March 2023, medical education professional organizations agreed to identify nutrition competencies for medical education.ObjectiveTo recommend nutrition competencies for inclusion in medical education to improve patient and population health.Evidence ReviewThe research team conducted a rapid literature review to identify existing nutrition-related competencies published between July 2013 and July 2023. Additional competencies were identified from learning objectives in selected nutrition, culinary medicine, and teaching kitchen curricula; dietetic core competencies; and research team–generated de novo competencies. An expert panel of 22 nutrition subject matter experts and 15 residency program directors participated in a modified Delphi process and completed 4 rounds of voting to reach consensus on recommended nutrition competencies, the level of medical education at which they should be included, and recommendations for monitoring implementation and evaluation of these competencies.FindingsA total of 15 articles met inclusion criteria for competency extraction and yielded 187 competencies. Through review of gray literature and other sources, researchers identified 167 additional competencies for a total of 354 competencies. These competencies were compiled and refined prior to voting. After 4 rounds of voting, 36 competencies were identified for recommendation: 30 at both undergraduate and graduate levels, 2 at the undergraduate level only, and 4 at the graduate level only. Competencies fell into the following nutrition-related themes: foundational nutrition knowledge, assessment and diagnosis, communication skills, public health, collaborative support and treatment for specific conditions, and indications for referral. A total of 36 panelists (97%) recommended nutrition competencies be assessed as part of licensing and board certification examinations.Conclusions and RelevanceThese competencies represent a US-based effort to use a modified Delphi process to establish consensus on nutrition competencies for medical students and physician trainees. These competencies will require an iterative process of institutional prioritization, refinement, and inclusion in current and future educational curricula as well as licensure and certification examinations.

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The Role of Nutrition in Chronic Disease

Abstract: According to the Centers for Disease Control and Prevention, six out of every ten adults in the United States have at least one chronic disease, and about four in ten have two or more chronic diseases [...]

Cited by 49 publications

References 15 publications

Biological Properties in Relation to the Health-Promoting Effects of Independent and Combined Garcinia mangostana Pericarp and Curcuma in Lean Wistar Albino Rats

Biological Properties in Relation to the Health-Promoting Effects of Independent and Combined Garcinia mangostana Pericarp and Curcuma in Lean Wistar Albino Rats

Challenges in ageing persons with haemophilia

Proposed Nutrition Competencies for Medical Students and Physician Trainees

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