The Role of Obesity as a Modifying Factor in Patients Undergoing Non‐Surgical Periodontal Therapy

Zuza, Elizângela Partata; Barroso, Eliane Marçon; Carrareto, Ana Luiza Vanzato; Pires, Juliana Rico; Carlos, Iracilda Zeppone; Theodoro, Letícia Helena; Toledo, Benedicto Egbert Corrêa de

doi:10.1902/jop.2010.100545

Cited by 74 publications

(148 citation statements)

References 29 publications

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“…These findings are in agreement with those of Zuza et al who suggested that obesity does not interfere with periodontal therapy response, even though it is a proinflammatory and metabolically active condition (35).…”

Section: Discussionsupporting

confidence: 93%

Lipid profile and high-sensitivity C-reactive protein levels in obese and non-obese subjects undergoing non-surgical periodontal therapy

Zuza¹,

Barroso²,

Fabricio³

et al. 2016

Journal of Oral Science

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Periodontal treatment may improve the metabolic control of dyslipidemia. The aim of this study was to evaluate the lipid profile and high-sensitivity C-reactive protein (hs-CRP) levels in obese and non-obese patients undergoing periodontal therapy. Patients with generalized chronic periodontitis were divided into obese (n = 28) and non-obese groups (n = 26). The periodontal parameters (visible plaque index, gingival bleeding index, probing depth, clinical attachment level, and bleeding on probing), anthropometric measurements (body mass index, waist circumference, and body fat), and serum analyses (triglycerides, total cholesterol, high-density lipoprotein, low-density lipoprotein, fasting glucose, glycated hemoglobin, and hs-CRP) were measured at baseline and 90 days after periodontal treatment. The results showed that the obese subjects presented alterations in triglycerides, total cholesterol, low-density lipoprotein, and hs-CRP at baseline when compared with non-obese patients (P < 0.05). Periodontal treatment could improve the periodontal parameters in both groups similarly (P > 0.05). Obese subjects showed a significant decrease in the levels of triglycerides, total cholesterol, low-density lipoprotein, and hs-CRP post-therapy (P < 0.05), while non-obese patients showed improvement only in hs-CRP (P < 0.05). In conclusion, periodontal treatment could improve the periodontal parameters and circulating hs-CRP in obese and non-obese subjects. Lipid profile was modified only in obese patients post-therapy. (J Oral Sci 58, [423][424][425][426][427][428][429][430] 2016)

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Section: Discussionsupporting

confidence: 93%

Lipid profile and high-sensitivity C-reactive protein levels in obese and non-obese subjects undergoing non-surgical periodontal therapy

Zuza¹,

Barroso²,

Fabricio³

et al. 2016

Journal of Oral Science

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“…Recent studies evaluating the effect of periodontal treatment on inflammatory mediators in obese patients (BMI ≥ 30 kg/m 2 ) reported a significant reduction in circulating pro-inflammatory cytokines (20)(21)(22). Gonçalves et al (23) reported less of a decrease in TNF-α levels in obese patients compared with non-obese patients following non-surgical periodontal treatment.…”

Section: Discussionmentioning

confidence: 99%

The clinical and systemic effects of periodontal treatment in diabetic and non-diabetic obese patients

et al. 2016

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“…Several studies (23)(24)(25)(26)(27) have examined periodontal outcomes after nonsurgical periodontal treatment (NSPT) for CP in obese patients. Although some studies reported that obesity did not affect clinical attachment gain or probing pocket depth (PPD) reduction after periodontal treatment (25,26,28), other studies showed that patients with a higher body mass index (BMI) had a poorer response to NSPT (19,24).…”

Section: Introductionmentioning

confidence: 99%

Effect of nonsurgical periodontal treatment on clinical periodontal variables and salivary resistin levels in obese Asians

et al. 2017

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This study investigated changes in periodontal outcomes after nonsurgical periodontal treatment (NSPT) and evaluated associations of change in salivary resistin level with periodontal outcomes in obese Malaysians with chronic periodontitis. Sixty-two obese adults with chronic periodontitis were randomly divided into a test group (n = 31), which received NSPT, and a control group (n = 31), which received no treatment. Plaque score (PS), gingival bleeding index (GBI), probing pocket depth (PPD), and clinical attachment loss (CAL) were measured at baseline and at 6 and 12 weeks after NSPT. Salivary resistin levels were evaluated by using an enzyme-linked immunosorbent assay. PS was significantly lower in patients who received NSPT than in the control group at 6 and 12 weeks (P < 0.05). In the NSPT group the percentages of sites with shallow and moderate pockets decreased significantly, but there was no significant change in deep pockets. Resistin levels significantly decreased after NSPT (P < 0.05). Change in salivary resistin level was not significantly associated with periodontal outcomes. In obese Malaysians, NSPT significantly improved PS and GBI, and improved PPD and CAL for shallow and moderately deep pockets but not for deep pockets. Salivary resistin level was not associated with improvement in either periodontal variable.

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The Role of Obesity as a Modifying Factor in Patients Undergoing Non‐Surgical Periodontal Therapy

Abstract: Obesity does not seem to play a negative role by interfering in the improvement of the periodontal clinical response or decreasing circulating proinflammatory cytokine levels after periodontal treatment.

Cited by 74 publications

References 29 publications

Lipid profile and high-sensitivity C-reactive protein levels in obese and non-obese subjects undergoing non-surgical periodontal therapy

Lipid profile and high-sensitivity C-reactive protein levels in obese and non-obese subjects undergoing non-surgical periodontal therapy

The clinical and systemic effects of periodontal treatment in diabetic and non-diabetic obese patients

Effect of nonsurgical periodontal treatment on clinical periodontal variables and salivary resistin levels in obese Asians

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