The role of oxygen saturation measurement and body mass index in distinguishing between non-apnoeic snorers and patients with obstructive sleep apnoea syndrome

Ünal, Murat; Öztürk, Levent; Kanık, Arzu

doi:10.1046/j.1365-2273.2002.00592.x

Cited by 7 publications

(4 citation statements)

References 14 publications

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“…3). This is consistent with previous findings in the medical literature, which highlight high BMI as an important risk factor for sleep-disordered breathing [14][15][16]. As was the case with age, singers were found to have significantly lower SSS values compared to non-singers when matched for BMI.…”

Section: Sss Vs Agesupporting

confidence: 92%

The effect of singing on snoring and daytime somnolence

Pai

Wolf

et al. 2008

Sleep Breath

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The objective of the study is to compare the prevalence and severity of snoring and daytime somnolence amongst semiprofessional choir singers and non-singers. It is a cross-sectional comparative study and the setting is at a tertiary otorhinolaryngology referral centre. Adult singers were recruited from two mixed-gender choirs in London. The control group consisted of healthy volunteers who do not sing. The weight and height of all participants were measured by a single investigator. A questionnaire was completed by each subject, and the snoring habit section completed by their spouses or partners. The snoring scale score (SSS) and Epworth Sleepiness Scale (ESS) were utilised to assess the severity of snoring and daytime somnolence, respectively. The mean age of the singers was 46.3 years (20:32, males to females) and the control group 43.3 years (23:32, males to females). There was no difference in body mass index (BMI; p = 0.180) and ESS score (p = 0.770) between singers and non-singers. Regression analysis showed no significant relationship between the number of years of singing and ESS score (p = 0.390) although there was a linear relationship between age and SSS for both singers (R (2) = 0.11; p = 0.02) and non-singers (R (2) = 0.20; p = 0.01). Based on the general linear model, singers have significantly lower SSSs compared to non-singers when adjusted for age (p = 0.0147), BMI (p = 0.0389) and both age and BMI (p = 0.0153). Singing practice may have a role in the treatment of snoring but does not appear to influence daytime somnolence.

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Section: Sss Vs Agesupporting

confidence: 92%

The effect of singing on snoring and daytime somnolence

Pai

Wolf

et al. 2008

Sleep Breath

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“…A study showed that BMI and DM are independent risk factors for OSAS, and central obesity may be more dangerous than BMI in this regard [29]. Another study showed that BMI is ineffective in determining the severity of OSAS [31]. In our study, BMI was similar in all OSAS severity groups.…”

Section: Resultssupporting

confidence: 57%

Can biomarkers predict the risk of cardiovascular disease in patients with obstructive sleep apnea syndrome?

Ölmez¹,

Tosun²,

Ünver³

et al. 2023

J Surg Med

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Background/Aim: Obstructive sleep apnea syndrome (OSAS) is a clinical syndrome characterized by recurrent partial or total obstruction of the upper airway. Cardiovascular disease (CVD) is more common in OSAS patients. Biomarkers can predict the progression of OSAS disease and the occurrence of CVD. Here we investigate the effects of age, gender, body mass index (BMI), comorbidities, neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), systemic inflammatory index (SII), atherogenic index of plasma (AIP), C-reactive protein-to-albumin ratio (CAR) and monocyte to HDL cholesterol (MHR) on the severity of OSAS and the occurrence of CVD in OSAS patients. Method: This cross-sectional study included 172 OSAS patients presenting to Erzincan Binali Yildirim University Mengucek Gazi Training and Research Hospital, Sleep Service between 01.01.2021 and 31.08.2022. Polysomnography (PSG) was applied to patients participating in the study, and routine complete blood and biochemistry tests were performed. Comorbidities and demographic data of the participants were recorded. Results: The frequency of CVD, chronic pulmonary disease (CPD) and hyperlipidemia increased as the severity of OSAS increased (P=0.005, P<0.001, P=0.016, respectively). As the severity of OSAS disease increased, only the MHR indices increased (P=0.009). When OSAS groups with and without CVD were examined, OSAS patients with CVD were older and had higher BMI (P<0.001, P=0.001, respectively). In addition, tended to be females with hyperlipidemia, diabetes mellitus (DM) and high Charlson Comorbidity Index (CCI) scores (all P<0.001). When the polysomnography of OSAS patients with CVD was evaluated, apnea-hypopnea index (AHI), non-rapid eye movement (NREM)-AHI (NREM-AHI), respiratory disorder index (RDI) and oxygen desaturation index (ODI) values were higher and sleep efficiency (SE) values were lower than patients with OSAS without CVD (P=0.002, P=0.002, P=0.003, P<0.001, P<0.001, respectively). Conclusion: CVD is common in OSAS patients. As the severity of OSAS increases, the risk of developing CVD increases. Elderly female OSAS patients with hyperlipidemic, DM, high BMI, and Charlson Comorbidity Index (CCI) constitute a relatively risky group for CVD. OSAS patients with high AHI, NREM-AHI, RDI, ODI, and low SE values should be monitored more closely for CVD.

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“…VEGF in turn is regulated by HIF in hypoxic cells [38]. In this respect, OSAS is characterized by arterial oxygen desaturation during sleep with severe nighttime hypoxia (60–80% oxygen saturation), presumably causing local tissue hypoxia [39, 40]. The occurrence of hypoxia is strengthened by the high levels of plasma VEGF reported in patients with OSAS [41,42,43].…”

Section: Discussionmentioning

confidence: 99%

Skeletal Muscle Morphology and Aerobic Capacity in Patients with Obstructive Sleep Apnoea Syndrome

Larsson

Kadi²,

Ulfberg³

et al. 2008

Respiration

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Background: Despite the fact that patients with obstructive sleep apnoea syndrome (OSAS) often have symptoms at the level of skeletal muscle such as fatigue, the question of whether the structural, cellular and functional properties of limb skeletal muscles are affected has not been fully examined. Objective: The aim was to examine physiological and muscular parameters in patients with OSAS and to assess the relationship between these parameters and the clinical symptoms. Method: Eighteen patients with OSAS and 16 controls participated. Aerobic capacity was assessed using a submaximal test. Fibre type distribution and fibre area were analyzed on muscle biopsies taken from the tibialis anterior. The microvascularization was assessed using the following parameters: (1) the number of capillaries per fibre (CAF), (2) CAF per fibre area (CAFA), (3) capillary to fibre perimeter exchange (CFPE) index, which represents the interface between muscle fibre and capillaries, and (4) length of capillary/perimeter of the fibre (LC/PF) index or capillary tortuosity, which represents the percent of muscle fibre perimeter in contact with the wall of the microvessel. Results: The OSAS group had significantly lower predicted relative maximal oxygen uptake (p = 0.0047) which was inversely correlated to the apnoea/hypopnoea index (AHI; r = –0.6, p = 0.017). There was a significantly higher CFPE index for slow type I fibres (p = 0.007) and fast type II fibres (p = 0.0126) and a significantly higher LC/PF index for type I fibres (p = 0.0003) and type II fibres (p = 0.0285) in OSAS patients compared to controls. Conclusion: OSAS patients have a higher muscle microvascularization and a lower aerobic capacity than controls. Furthermore the aerobic capacity was inversely correlated to AHI.

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The role of oxygen saturation measurement and body mass index in distinguishing between non-apnoeic snorers and patients with obstructive sleep apnoea syndrome

Cited by 7 publications

References 14 publications

The effect of singing on snoring and daytime somnolence

The effect of singing on snoring and daytime somnolence

Can biomarkers predict the risk of cardiovascular disease in patients with obstructive sleep apnea syndrome?

Skeletal Muscle Morphology and Aerobic Capacity in Patients with Obstructive Sleep Apnoea Syndrome

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