The Role of Papaya Dressings in the Man Agement of Diabetic Foot Ulcers: A Prospective Study

Rajaram, Bapurapu; Venkanna, Madipeddi; Kumaraswamy, Boda; Kumar, Dodda Ramesh; Maripeddi, Karthik; Puligilla, Shankaraiah; Reddy, Sridhar

doi:10.18410/jebmh/2015/996

Cited by 3 publications

(2 citation statements)

References 16 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…6(7%) patients required further debridement, and 4(4%) required amputation. 11 In another investigation, hydrogel and saline had comparable mean slough at all intervals (p>0.050). The mean Slough decrease on day five (6.93±6.14% vs. 4.37±2.96%; p=0.045), day ten (15.22±7.40% vs9.10±7.00%; p=0.002), and day fifteen (21.57±8.71% vs 15.90±8.11%; p=0.012) was considerably higher than group B.…”

Section: Introductionmentioning

confidence: 90%

Comparison of Hydrogel and Papaya Dressings in the Treatment of Diabetic Foot Ulcers

Rizwan¹,

Rasheed²,

Mirza³

et al. 2023

PJMHS

View full text Add to dashboard Cite

Diabetes mellitus is the most common metabolic problem all over the world. Over 150 million people worldwide, are affected with this problem.1, 2 In Pakistan, the prevalence of diabetic patients are between 7.6% to 11%.3. Objective and Methodology: The aim of this study is to compare the relative efficacy of hydrogel and papaya dressings for diabetic foot ulcers. Patients from the General Surgery Department at Mayo Hospital in Lahore were 114 in total. Patients were randomized into: group H, who received hydrogel dressings, and group P, who received papaya dressings. Both dressings were done in ward for 20 days, every 48 hours and if wound healing occurred earlier and slough decreased then dressings were stopped and patient was discharged. The wound was assessed by photographic wound assessment tool (PWAT). Results: In Group P, mean age of patients was 52.98±8.90 and in Group H, mean age of patients was 50.98±9.62. In Group P, 34(59.6%) patients were male and 23(40.4%) were female. While in Group H 29(50.9%) patients were male and 28(49.1%) were female patients. We used Wound Assessment tool “PWAT” to compare the efficacy of these two treatment regimes. As per final “PWAT” score hydrogel dressing is more effective as compared to Papaya dressing for diabetic wound healing. i.e. Group P (Papaya dressing): 5.09±1.65 vs. Group H (hydrogel Dressing): 6.02±1.78, p-value=0.005 Conclusion: Depending upon the outcomes of this research, it can be concluded that hydrogel dressing is more useful than papaya dressing for treating diabetic wound. Although papaya dressing also have a beneficial effect on diabetic wound but still its efficacy is less as compared to hydrogel dressing Keywords: Papaya, Hydrogel, Dressing, Diabetic Foot, Wounds, Ulcer.

show abstract

Section: Introductionmentioning

confidence: 90%

Comparison of Hydrogel and Papaya Dressings in the Treatment of Diabetic Foot Ulcers

Rizwan¹,

Rasheed²,

Mirza³

et al. 2023

PJMHS

View full text Add to dashboard Cite

show abstract

“…Unripe papaya is a known source of the enzyme papain which has been used for enzymatic escharolysis and sloughectomy. [ 5 , 6 , 7 ] It is both effective and safe in wound bed preparation. This, however, is not in common practice in our region where papaya ( Carica papaya), locally known as pawpaw, is readily available and affordable.…”

Section: Introductionmentioning

confidence: 99%

Wound Bed Preparation using Nonsurgical Methods: A Prospective Comparative Study of Honey versus Unripe Papaya (Carica papaya)

Nnadozie,

Maduba,

Modekwe

et al. 2023

Annals of African Medicine

View full text Add to dashboard Cite

Background: The rapidity of wound bed preparation is determined in part by the type of dressing agent employed. The extension phase in which the wound is characterized by the presence of sloughs and eschar and microbial invasion could be managed nonsurgically. Objective: The objective of this study was to compare the rapidity of wound bed preparation using unripe papaya versus honey. Materials and Methods: Sixty-four patients were assigned into two equal groups, each dressed, respectively, with unripe papaya or honey. All selected patients were monitored for eschar separation and bacterial clearance time. Data obtained with a pro forma were analyzed with SPSS version 25. Results: Unripe papaya dressing had a mean eschar separation time of 5.53 ± 2.20 days and bacterial clearance time of 6.81 ± 3.64 days compared to the honey group which had an eschar separation time of 30.09 ± 27.90 days and bacterial clearance time of 15.33 ± 13.62 days. P <0.001 and P < 0.001, respectively, in comparing both outcome measures between the two groups. There was a statistically significant difference in both eschar/slough separation time and bacterial clearance time both in favor of the group prepared with unripe papaya. Conclusion: The use of unripe papaya was superior to honey in wound bed preparation with respect to eschar/slough separation, bacterial clearance ultimately resulting in reduced length of hospital stay.

show abstract

The Use of Unripe Pawpaw for Wound Bed Preparation Following Radiation-Induced Sacral Ulcer

Nwankwo

Maduba

Modekwe

et al. 2021

Nigerian Journal of Medicine

View full text Add to dashboard Cite

Radiation wounds are very difficult to manage due to poor vascular status, excessive matrix metalloproteinases, and abnormal myofibroblast function. Such wound beds do not adequately support conventional resurfacing as do nonradiate beds. We present a 46-year-old female with a sacral radiation ulcer, which had earlier failed to support flap cover on two instances after bed preparation with conventional honey dressing and negative pressure dressing, but was subsequently successfully managed with unripe pawpaw wound bed preparation. A re-elevation of the right gluteal myocutaneous flap proved successful and satisfactory. The finding may have resulted from both enzymatic properties of unripe pawpaw and its ability to break the biofilms and to locally supply the ascorbic acid necessary for collagen synthesis and granulation tissue formation.

show abstract

The Role of Papaya Dressings in the Man Agement of Diabetic Foot Ulcers: A Prospective Study

Cited by 3 publications

References 16 publications

Comparison of Hydrogel and Papaya Dressings in the Treatment of Diabetic Foot Ulcers

Comparison of Hydrogel and Papaya Dressings in the Treatment of Diabetic Foot Ulcers

Wound Bed Preparation using Nonsurgical Methods: A Prospective Comparative Study of Honey versus Unripe Papaya (Carica papaya)

The Use of Unripe Pawpaw for Wound Bed Preparation Following Radiation-Induced Sacral Ulcer

Contact Info

Product

Resources

About