The role of positive nerve root sedimentation sign in the treatment of patients undergoing lumbar disc herniation

Deng, Luoyi; Yang, Hua; Liu, Miao; Liang, Tihong; Wang, Fengyan; Xu, Ning; Sun, Hong

doi:10.1080/02688697.2021.1923652

Cited by 2 publications

(2 citation statements)

References 9 publications

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“…12 Deng et al found better LBP relief and functional improvement in NRSS-positive patients who underwent lumbar disc herniation surgery. 24 Fazal et al and Badve et al stated that the NRSS may help in making the decision for surgical treatment of LSS. 25,26 Conversely, Barz et al reported that the NRSS could not predict surgical success in the treatment of LSS, but NRSS positivity could be associated with limited outcomes of conservative treatments.…”

Section: Discussionmentioning

confidence: 99%

The Relationship between Nerve Root Sedimentation Sign and Cerebrospinal Fluid Signal Loss Sign with Treatment Success in Patients Undergoing Lumbar Epidural Injections

KAYA

2023

J PMR Sci

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This study aimed to determine whether nerve root sedimentation sign (NRSS) and cerebrospinal fluid signal loss sign (CFSLS) could predict the short-term outcomes of interlaminar lumbar epidural steroid injections (ILESIs) in the treatment of lumbar spinal stenosis (LSS). Material and Methods: In this retrospective study, a total of 73 patients who were diagnosed with LSS and underwent ILESIs were included. Successful pain management was determined as a decrease of ≥50% in visual analogue scale scores 1 month after ILESIs. The patients were divided into successful and unsuccessful treatment groups and the findings of NRSS and CFSLS were compared between the two groups. Results: While 62.2% of patients in the successful group had a positive NRSS, 32.1% of patients in the unsuccessful group had a positive NRSS and the difference was statistically significant (p=0.017). The CFSLS was positive for 62.2% of patients in the successful group compared to 57.11% of patients in the unsuccessful group and this difference was not statistically significant (p=0.806). Conclusion: One month after ILESI, low back/leg pain decreased more in patients with positive NRSS than in patients with negative NRSS. The NRSS might be a valuable sign in predicting the success of ILESI treatment among patients with LSS.

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Section: Discussionmentioning

confidence: 99%

The Relationship between Nerve Root Sedimentation Sign and Cerebrospinal Fluid Signal Loss Sign with Treatment Success in Patients Undergoing Lumbar Epidural Injections

KAYA

2023

J PMR Sci

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“…The cartilaginous and bony end-plates are the thin layers of hyaline cartilage placed between the IVD and the adjacent vertebral bodies, which is the main approach for nutrient supply to all IVD cells through diffusion, as well as removal of waste products. With the development of IDD, the annulus fibrosus will be broken, with the consequence of the protrusion of the nucleus pulposus (NP), which is called lumbar disc herniation (LDH) Tseng;Sun;Chang and Chen, 2021;Deng et al, 2021). Patients with LDH usually present with symptoms such as pain, numbness, and weakness, which have a significant negative influence on their social functions.…”

Section: Introductionmentioning

confidence: 99%

The Thermosensitive Injectable Celecoxib-Loaded Chitosan Hydrogel for Repairing Postoperative Intervertebral Disc Defect

Tang

et al. 2022

Front. Bioeng. Biotechnol.

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Percutaneous endoscopic lumbar discectomy has been widely used in clinical practice for lumbar spine diseases. But the postoperative disc re-herniation and inflammation are the main reason for pain recurrence after surgery. The postoperative local defect of the intervertebral disc will lead to the instability of the spine, further aggravating the process of intervertebral disc degeneration. In this work, we successfully synthesized the thermosensitive injectable celecoxib-loaded chitosan hydrogel and investigated its material properties, repair effect, biocompatibility, and histocompatibility in in vitro and in vivo study. In vitro and in vivo, the hydrogel has low toxicity, biodegradability, and good biocompatibility. In an animal experiment, this composite hydrogel can effectively fill local tissue defects to maintain the stability of the spine and delay the process of intervertebral disc degeneration after surgery. These results indicated that this composite hydrogel will be a promising way to treat postoperative intervertebral disc disease in future clinical applications.

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The role of positive nerve root sedimentation sign in the treatment of patients undergoing lumbar disc herniation

Cited by 2 publications

References 9 publications

The Relationship between Nerve Root Sedimentation Sign and Cerebrospinal Fluid Signal Loss Sign with Treatment Success in Patients Undergoing Lumbar Epidural Injections

The Relationship between Nerve Root Sedimentation Sign and Cerebrospinal Fluid Signal Loss Sign with Treatment Success in Patients Undergoing Lumbar Epidural Injections

The Thermosensitive Injectable Celecoxib-Loaded Chitosan Hydrogel for Repairing Postoperative Intervertebral Disc Defect

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