The role of probiotics in preventing dental caries

Shakib, Pegah; Rouhi, Samaneh; Zolfaghary, M R

doi:10.29252/pbp.2.1.55

Cited by 7 publications

(5 citation statements)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Looking at Table (6), the mean concentration of the control negative group was 486 ±57 ng/l but the control positive group showed a significant reduction to 417±129 ng/l on day 3 but increased gradually till day 7 reaching 738±22 ng/l. On the other hand, the treated group showed a lower concentration of this parameter on 3PO at 337±39 than the control positive, however, it revealed a good rise to 529±9 ng/L at 7PO and reached a level near that of the control negative group that could be considered as a normal state as illustrated in Figure (2).…”

Section: Serum Il-10 Resultsmentioning

confidence: 86%

“…The data in Table (1) displayed substantial changes in IL-1 β levels among all groups as the P value was 0.000 in the Kruskal-Walis test. In Table (2), Mann-Whitney tests were performed between every two independent groups and also gave significant values less than 0.05 indicating changes in concentrations of this parameter.…”

Section: Serum Il-1 β Resultsmentioning

confidence: 99%

“…They can also stop pathogenic bacteria from adhering to cells and invading the environment. Additionally, they work well to control the systemic and local immune systems [2].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

The Impact of Oral Administration of Systemic Probiotics “Lactobacillus rhamnosus” on IL-1β and IL-10 Levels and Wound Healing of Oral Mucosa in Rabbits

Attarbashi,

Al-Mashhadane

2024

Egyptian Journal of Veterinary Sciences

View full text Add to dashboard Cite

HE LACK of effective treatment for oral wounds has motivated researchers to explore alternative treatments to improve intraoral wound healing. Aims: This study investigates the beneficial role of probiotics Lactobacillus rhamnosus in oral wounds. Material and Method: Twenty-five rabbits were included and categorized into three groups; The control negative group (five rabbits) who had no surgery and no treatment. The control positive group (ten rabbits), was subdivided equally into two subgroups (a and b) they had an incision of 1cm in their buccal mucosa but had not received any treatment. The third group (ten rabbits), the treatment group, was also subdivided into (a and b) and received probiotic drops of Lactobacillus rhamnosus to be swallowed once daily starting from day 1 till the day of euthanizing. The rabbits from group I and subgroups IIa and IIIa were sacrificed on the third day. All rabbits of subgroups IIb and IIIb were euthanized on the seventh day. Serum samples were collected and their mucosal tissue at wound sites was removed for histological analysis. Results: The serum levels of proinflammatory Interluekin-1β and antiinflammatory Interluekin-10 in the third-day groups presented a significant difference, while in the seventh-day groups, the results of the treated group showed a higher level of IL-10 than IL-1B indicating less inflammation. In microscopic inspection, the untreated group revealed more inflammatory signs on day 3 than the treated group. On day 7, the treated group presented very good signs of healing as compared to the control-positive group. Conclusion: Systemic probiotic Lactobacillus rhamnosus enhances the wound healing of oral mucosa.

show abstract

Section: Serum Il-10 Resultsmentioning

confidence: 86%

Section: Serum Il-1 β Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The Impact of Oral Administration of Systemic Probiotics “Lactobacillus rhamnosus” on IL-1β and IL-10 Levels and Wound Healing of Oral Mucosa in Rabbits

Attarbashi,

Al-Mashhadane

2024

Egyptian Journal of Veterinary Sciences

View full text Add to dashboard Cite

show abstract

“…Tooth decay is commonly caused by acid production of numerous micro-organisms in the mouth. The use of probiotic bacteria is an alternative therapy for micro-organism-mediated diseases 3 .…”

Section: Introductionmentioning

confidence: 99%

Effects of Dental Pulp Stem Cell Preconditioning on Osteogenesis using Conditioned Media of Probiotics Bacteria

Amini¹,

Rezvani²,

Bakhtiari³

et al. 2023

AJMB

View full text Add to dashboard Cite

Background: Stem cells are used to treat numerous diseases; however, their lifespan is rather short. Factors such as probiotics affect and improve various cell lineage efficacies. The aim of this study was to investigate the effects of probiotics-conditioned media on dental pulp stem cell potentials in osteogenesis. Methods: The experiment was initiated by culturing Lactobacillus casei and Lactobacillus acidophilus probiotics as well as DPS-7 cells. Bacterial supernatants were separated and concentrated as the conditioned media. The DPS-7 cells were treated with various concentrations of the conditioned media. Furthermore, MTT assay and alkaline phosphatase activity were used. The mRNA expression of three genes (bFGF, EGF-β and BMP-2) involved in osteogenesis was analyzed using a real-time polymerase chain reaction. Results: The response of dental pulp stem cells to probiotics preconditioning promoted cell proliferation, increased alkaline phosphatase activity and upregulated bFGF and BMP-2 gene expression. Increased expression was significant for BMP-2 and moderate for bFGF; however, it was non-significant for EGF-β. The use of the two probiotics was the most effective. Conclusion: In general, synergism of the combined probiotics preconditioning induces differentiation of DPS-7 cells into osteoblasts most effectively.

show abstract

“…According to the findings of Riset Kesehatan Dasar conducted in 2018, the percentage of dental and oral health concerns was 57.6% [1]. Pulpitis is a dental and oral health condition that manifests frequently and results in discomfort [2]. According to study conducted in Narayana, 77.2% of respondents had suffered pulpitis [3].…”

Section: Introductionmentioning

confidence: 99%

Untitled

2023

J. Med. Chem. Sci.

View full text Add to dashboard Cite

To determine the effective volume of eugenol on day 3 in the inflamed pulp. Methods: Experimental research with a posttest-only control group design The experimental animals used were 28 male Sprague-Dawley rats. The maxillary right molar tooth was prepared with a size of 1 mm and a depth of 1 mm. Eugenol was dropped on cotton pellets according to the treatment group, namely 0.1 µL, 0.08 µL, and 0.02 µL, and aquadest as a negative control was then put into the cavity and closed with a temporary seal. Rats were decapitated after 3 days, prepared, and stained with hematoxylin and eosin. Results were read with a 100x magnification microscope at 3 fields of view and with imageJ software. Results: The average number of macrophages in the cotton pellet application group with 0.1 µL eugenol volume was 22, the 0.08 µL eugenol volume group was 6.71, the 0.02 µL eugenol volume group was 44.43, and the negative control group was 34.29. The results of the one-way ANOVA test showed a significance of 0.000 (p<0.05). Conclusion: Eugenol volumes of 0.08 µL had the lowest average number of macrophages compared to eugenol volumes of 0.01 µL and 0.02 µL, and based on the post hoc test, there was a significant difference (p<0.05).

show abstract

The role of probiotics in preventing dental caries

Cited by 7 publications

References 28 publications

The Impact of Oral Administration of Systemic Probiotics “Lactobacillus rhamnosus” on IL-1β and IL-10 Levels and Wound Healing of Oral Mucosa in Rabbits

The Impact of Oral Administration of Systemic Probiotics “Lactobacillus rhamnosus” on IL-1β and IL-10 Levels and Wound Healing of Oral Mucosa in Rabbits

Effects of Dental Pulp Stem Cell Preconditioning on Osteogenesis using Conditioned Media of Probiotics Bacteria

Untitled

Contact Info

Product

Resources

About