The role of psychopathology in perceiving, reporting and treating intermittent claudication: a systematic review

Depressive symptomatology and personality traits in patients with symptomatic and asymptomatic peripheral arterial disease

“…On the one hand, our findings are consistent with prior studies indicating a larger prevalence of depression in individuals with PAD than in those without [7]. On the other hand, our results indicate a higher prevalence of depression in the 'clear PAD positive' subgroup of our patients (63%) than what was found in studies included in Sliwka's systematic review, where the rate of PAD-symptomatic patients presenting with depressive symptoms varied between 9.4 and 53% [5]. This difference in depressive symptom prevalence might be partially related to the different assessment approaches to depression in previous studies [5], but most likely it is not independent of the elevated level of depression in the Hungarian general population [26] either.…”

“…On the other hand, our results indicate a higher prevalence of depression in the 'clear PAD positive' subgroup of our patients (63%) than what was found in studies included in Sliwka's systematic review, where the rate of PAD-symptomatic patients presenting with depressive symptoms varied between 9.4 and 53% [5]. This difference in depressive symptom prevalence might be partially related to the different assessment approaches to depression in previous studies [5], but most likely it is not independent of the elevated level of depression in the Hungarian general population [26] either. It is worth mentioning that very few previous studies have considered asymptomatic PAD patients, who also reported higher rate of depressive symptoms in the present study (compared to the 'clear PAD negative' subgroup) similar to patients with atypical leg symptoms in the study of Smolderen and colleagues [27] who reported more impaired mood than their asymptomatic counterparts.…”

“…Traditional risk factors of PAD include hypertension, smoking and hyperlipidemia but there is an increasing attention on the psychological aspects and their role in the pathomechanism of PAD. Psychosocial factors might also influence the way in which the symptoms of PAD are reported, coped with, and treated [5]. Depression is the most frequently assessed psychosocial factor among patients with PAD.…”

“…To date, extant studies on personality among patients with PAD have focused on individual, isolated personality traits or specific personality patterns: Type-D personality [10], Type A Behavior Pattern [11] or hostile personality [12]. However, no studies have been devoted to a better understanding of the relationships between PAD and a wider range of personality traits simultaneously, which led to the authors of a related systematic review to explicitly call for the development of such a research agenda [5] including Big Five personality traits [13].…”

Depression among predictors of intermittent claudication: A cross-sectional study

“…These patients have a 20% higher risk of experiencing a cerebrovascular event, which highlights the system-disease nature of LEAD [5]. Traditional risk factors of LEAD include hypertension, diabetes, smoking, and hyperlipidemia; however, the implications of psychological aspects and their roles in the pathogenesis of LEAD [6] are now being considered. For instance, among patients with IC, symptoms of depression have been identified as a personal barrier to exercise [7].…”