Social isolation and loneliness have a significant impact on people' s physical and mental health, as well as society as a whole. Consequently, numerous studies have examined interventions to alleviate social isolation and loneliness and have shown that they have some effect. This paper first briefly reviewed studies that have examined the influences of social isolation and loneliness and intervention studies aimed at alleviating them. Then, after pointing out the limitations of previous intervention studies, it was emphasized that research on primary prevention of social isolation and loneliness is needed, yet little has been done. Finally, based on research findings on, social pain, relational mobility, and social networks, we argued that for the primary prevention of social isolation and loneliness, providing a variety of social networks and increasing freedom of movement between these networks are important.