2018
DOI: 10.2139/ssrn.3296680
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The Role of Saline Irrigation Prior to Wound Closure in the Reduction of Surgical Site Infection: A Systematic Review and Meta-Analysis

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Cited by 3 publications
(5 citation statements)
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“…In addition, further studies are needed to deliver a clinically meaningful difference in the results. This was suggested in other meta‐analyses, which showed similar effects 4,48‐52 . This needs additional examination and clarification because no clear reasoning was found to clarify these outcomes.…”
Section: Discussionmentioning
confidence: 89%
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“…In addition, further studies are needed to deliver a clinically meaningful difference in the results. This was suggested in other meta‐analyses, which showed similar effects 4,48‐52 . This needs additional examination and clarification because no clear reasoning was found to clarify these outcomes.…”
Section: Discussionmentioning
confidence: 89%
“…This was suggested in other meta‐analyses, which showed similar effects. 4 , 48 , 49 , 50 , 51 , 52 This needs additional examination and clarification because no clear reasoning was found to clarify these outcomes. Well‐designed clinical trials are also required to evaluate these factors with the blend of diverse ages, gender, and ethnicity; as our meta‐analysis study could not answer whether these factors are related to the outcomes.…”
Section: Discussionmentioning
confidence: 99%
“…In this study, we did not investigate the effect that the irrigation fluids have on outcomes other than bleeding time. Further studies are needed to show how these fluids compare with the standard of care, and this may be relevant in fields, such as orthopedics, where the association of irrigation fluid with wound infection and delayed healing has been well investigated (6,7,(9)(10)(11).…”
Section: Figmentioning
confidence: 99%
“…However, there were two important caveats: HWI uses pure water, which causes severe cellular damage and rupture of human nasal epithelial cells (4), and water heated to 52°C or higher results in epithelial necrosis of animal nasal mucosal cells (5). Although several studies have looked into the effect of different irrigation fluids and additives on surgical outcomes, such as SSIs (6,7), perioperative hypothermia (8), wound closure (9,10), fracture healing (11), and tumor recurrence and metastasis (12)(13)(14), their influence on bleeding control has not been adequately explored.…”
Section: Introductionmentioning
confidence: 99%
“…Intra-operatively, intra-peritoneal contamination can be diminished by copious wash-out of the peritoneal cavity and appropriate placement of drains (9) . Irrigation and drainage of the subcutaneous tissues before wound closure by antiseptic solutions is also advocated (10)(11)(12)(13) .…”
Section: Introductionmentioning
confidence: 99%