The Role of Salivary Immunoglobulin a in the Prevention of the Upper Respiratory Tract Infections in Athletes – An Overview

The Effects of a 36-Hour Mixed Task Ultraendurance Race on Mucosal Immunity Markers and Pulmonary Function

“…The present study extends the knowledge surrounding salivary IgA and ultraendurance events to include events based upon both sleep deprivation and varied forms of exercise. Work needs to continue in these areas, as recent reviews by Orysiak et al 28 While most studies in the literature have focused on the dimeric molecule salivary IgA, in the present study an additional immunoglobulin secretory IgA type 1 was assessed. Although no significant differences were revealed for this immunoglobulin, further work should be conducted in this area as this form of exercise might negatively affect the expression of this molecule.…”

“…The present study extends the knowledge surrounding salivary IgA and ultraendurance events to include events based upon both sleep deprivation and varied forms of exercise. Work needs to continue in these areas, as recent reviews by Orysiak et al 28 on sIgA and upper respiratory tract infection and by Walsh et al 29 on exercise and immune function suggest that reductions in IgA are associated with increased risk of upper respiratory tract infection.…”

Expression of SCGB1C1 gene as a potential marker of susceptibility to upper respiratory tract infections in elite athletes – a pilot study

“…Some studies have suggested that cytokine gene polymorphisms (for example for IL-10 and IL-6) may contribute to the variable risk of development of URTI in highly trained athletes [ 19 , 20 ]. Previous studies have also demonstrated that low levels of sIgA or of sIgA fractions may be associated with upper respiratory tract infections in athletes [ 10 ], but the role of IL-5 in URTI is not clear [ 19 , 21 , 22 ].…”

“…sIgA plays a key role in the mucosa-associated lymphoid tissue (MALT), which forms the first line of defence against infections of the upper respiratory tract [ 7 ]. Previous research has shown that exercise influences the concentration/secretion rate of sIgA [ 8 , 9 ], and that a low level of sIgA could be associated with increased frequency of upper respiratory tract infections in athletes [ 10 ]. The concentration of sIgA in saliva depends on the synthesis of this immunoglobulin and the efficiency of its transport across the mucosa.…”

Pertussis outbreak in Polish shooters with adverse event analysis

“…The modern sport is highly competitive, and all factors impairing even slightly the athlete’s performance during games reduce the chance of winning. In addition to different injuries, infections are the most common reason for giving up training altogether or reducing its volume and intensity, as well as a lack of opportunities to participate in sports competitions [ 7 – 12 ]. Since pathogens vary in nature and can be transmitted through different routes – inhalation of airborne infectious agents, skin contact or injuries, ingestion of contaminated food or water, via vectors (e.g.…”