The role of serum red blood cell distribution width level in predicting the short term mortality of community-acguired pneumonia, acute attack chronic pulmonary disease, and acute pulmonary thromboembolism

Aydemir, Semih; Hoşgün, Derya

doi:10.38053/acmj.888740

Cited by 1 publication

(3 citation statements)

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“…Similar range and/or median for NLR, RDW, procalcitonin, NAR, and BAR has been reported in pneumonia and sepsis patients. [17][18][19][20][21] Factors such as time of sampling, type of equipment and reagents used should be considered for these laboratory results.…”

Section: Resultsmentioning

confidence: 99%

“…four hours after admission. 17 RDW is a nonspecific inflammatory marker, elevated in conditions such as heart failure, stroke, peripheral arterial disease, and chronic lung disease. 13 Recent study found that RDW >15 affects red blood cell deformability.…”

Section: Resultsmentioning

confidence: 99%

“…Suggestion was made to evaluate other inflammatory indicators such as CRP and gammaglutamyl transferase along with RDW to provide better information of inflammatory status. 17 Procalcitonin has been widely used to help differentiate bacterial infections from non-infectious conditions, predict severity, mortality, and monitor patients, especially CAP and sepsis. Our study found statistically significant relationship between procalcitonin and mortality with 3.94-fold higher likelihood of mortality (Table 8).…”

Section: Resultsmentioning

confidence: 99%

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Relationship between neutrophil to lymphocytes ratio, red cell distribution width, procalcitonin, neutrophil to albumin ratio, and bun to albumin ratio with mortality of severe cap patients with septic shock

Cahyani,

Candrawati,

Arisanti

et al. 2024

Int J Adv Med

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Background: Septic shock is one of severe community-acquired pneumonia (CAP) complication with high mortality. Various laboratory parameters had been associated with poor outcome including neutrophil-to-lymphocyte ratio (NLR), red cell distribution width (RDW), procalcitonin, neutrophil to albumin ratio (NAR), and bun to albumin ratio (BAR). This study aimed to know the relationship between inflammatory markers with mortality of severe CAP patients with septic shock. Methods: This study is an observational analytic study using a cohort retrospective design conducted in Prof. I.G.N.G. Ngoerah General Hospital over a 3 years’ period (January 2020 to July 2023). The relative risk (RR) values showed relative risk of each parameter to mortality. Results: Of total 73 subjects, mortality was found in 68.5%. Male predominance was found (65.8%). Comorbid disease was reported in 69 subjects (94.5%), most found was cardiovascular disease (63%). Majority of the subjects did not have history of prior antibiotics use (86.3%). In multivariate analysis, it was found that NLR with cutoff ≥16.5 (p value 0.044; 95% CI 1.039-14.011; RR 3.816), procalcitonin ≥1.82 (p value 0.029; 95% CI 1.148-13.560; RR 3.945), and BAR ≥8.13 (p value 0.003; 95% CI 1.961-21.912; RR 7.399) are associated with mortality. There was no relationship between RDW ≥14.65 (p value 0.159; 95% CI 0.658-12.877) and NAR ≥4.5 (p value 0.436; 95% CI 0.429-7.106) with mortality in this study. Conclusions: Mortality of severe CAP patients with septic shock in this study is high. Higher NLR, procalcitonin, and BAR values have a significant relationship with mortality of severe CAP patients with septic shock.

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