The Role of Skin Tightening in Improving Cellulite

Hexsel, Dóris; Hexsel, Camile L.

doi:10.1097/dss.0000000000000204

Cited by 16 publications

(13 citation statements)

References 17 publications

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“…Increasing strength and elasticity of the dermis and superficial fascia are important aims when treating skin laxity to improve the appearance of cellulite; 21 such approaches require stimulation of new collagen formation and subsequent dermal remodeling. Two procedures that have unequivocally demonstrated collagen-stimulating properties and improvements in skin laxity in a variety of aesthetic indications are microfocused ultrasound with visualization (MFU-V, Ultherapy; Ulthera, Inc., Mesa, Ariz.), 22 – 31 and injection with calcium hydroxylapatite (CaHA, Radiesse; Merz North America, Inc., Raleigh, N.C.).…”

Section: Introductionmentioning

confidence: 99%

Microfocused Ultrasound with Visualization and Calcium Hydroxylapatite for Improving Skin Laxity and Cellulite Appearance

Casabona

Pereira

2017

Plastic and Reconstructive Surgery - Global Open

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Background:Age-associated skin laxity contributes to worsening of cellulite appearance. This study evaluated the effects of microfocused ultrasound with visualization (MFU-V; Ultherapy) in combination with diluted calcium hydroxylapatite (CaHA; Radiesse) on cellulite appearance and on neocollagenesis.Methods:Twenty women (18–55 years old) with skin laxity and moderate-to-severe cellulite on the buttocks and thighs were retrospectively enrolled. MFU-V was applied using 4 and 7 MHz transducers (25 lines/transducer/site) and immediately followed by subdermal CaHA injection (1 ml/buttock or thigh). Photographs at baseline and 90 days were assessed by 2 independent, blinded evaluators using a 5-item cellulite severity scale. One subject scheduled for thighplasty received treatment with 6 different CaHA dilutions (0.3 ml/5 cm2) followed by MFU-V. Tissue specimens from each dilution site were examined under polarized light microscopy to assess neocollagenesis.Results:Both evaluators reported statistically significant improvements compared with baseline for each item on the cellulite severity scale (P < 0.001) with a 4.5-point improvement in mean overall score (P < 0.001) after a single MFU-V/CaHA treatment. At 90 days, histologic analysis showed peak neocollagenesis in samples treated with the 1:1 dilution, whether with CaHA alone or in combination with MFU-V. The highest conversion of collagen type III into collagen type I at month 3 occurred in samples injected with 1:1 and 1:0.6 CaHA dilutions without subsequent MFU-V treatment. Both procedures were well tolerated, and subject satisfaction was high.Conclusions:Combination treatment with MFU-V and diluted CaHA is effective for improving skin laxity and the appearance of cellulite on the buttocks and upper thighs.

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Section: Introductionmentioning

confidence: 99%

Microfocused Ultrasound with Visualization and Calcium Hydroxylapatite for Improving Skin Laxity and Cellulite Appearance

Casabona

Pereira

2017

Plastic and Reconstructive Surgery - Global Open

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“…RF has also been reported to increase local blood flow and to affect subcutaneous adipocytes, inducing their apoptosis . All this leads to overall tightening and reshaping of the treated area . The application of intense mechanical waves of short duration (μs) and intensities of around 10 MPA improves blood and lymphatic microcirculations, causes neovascularization, promotes lipolysis, and increases collagen fiber density, as well as improves skin elasticity and activates fat‐splitting enzymes .…”

Section: Introductionmentioning

confidence: 99%

Clinical evaluation of simultaneously applied monopolar radiofrequency and targeted pressure energy as a new method for noninvasive treatment of cellulite in postpubertal women

Fritz

Sălăvăstru

Gyurova

2018

J of Cosmetic Dermatology

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“…Omitted morphological items included orange peel, mattress and cottage cheese appearances, and other subjective measurements precisely developed for the buttock's region. The overall scores ranged from 0 to 9 and overall classifications of severity included absent (0), mild (1-3), moderate (4-6) and severe (7)(8)(9).…”

Section: Methodsmentioning

confidence: 99%

“…[4][5][6] Laxity, or sagging of the skin, further aggravates the alterations from the cellulite. 7 Currently, there are various procedures available for the treatment of cellulite in the region of the buttocks and postero-lateral thigh. 8,9 The skin above the knee is an area with increasing demand for treatment and, to date, there are very few treatment options proposed.…”

Section: Introductionmentioning

confidence: 99%

A validated photonumeric cellulite severity scale for the area above the knees: the knee cellulite severity score

Longhitano

Galadari

Cascini³

et al. 2020

Acad Dermatol Venereol

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Background Treatment for cellulite above the knees is increasingly requested. However, a classification of cellulite of this area has not yet been developed. Objective To validate the proposed knee cellulite severity score (KCSS) for the assessment of cellulite and skin laxity above the knee. Materials and methods Based on standardized photographs of cellulite and skin laxity above the knees of 57 females (114 knees), three key morphological aspects of cellulite were identified. A photonumeric KCSS was developed and validated by three independent assessors. Results The three key cellulite morphological features (number of depressions, depth of depressions and presence of laxity) are each graded from 0 to 3, producing a classification of no lesions (0), mild (1–3), moderate (4–6) and severe (7–9). Evaluators at different time points repeated similar classifications (intraclass correlation coefficient >0.9), which were also similar among the assessors (inter‐observer reliability >0.9). All three key morphological aspects were deemed necessary, and positively contributed, to the overall scale (item‐total correlation analysis values >0.89, P < 0.05). Conclusions The KCSS is a consistent, comprehensive, reliable, and reproducible tool for standardized and objective assessment of the severity of cellulite and skin laxity above the knees.

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The Role of Skin Tightening in Improving Cellulite

Cited by 16 publications

References 17 publications

Microfocused Ultrasound with Visualization and Calcium Hydroxylapatite for Improving Skin Laxity and Cellulite Appearance

Microfocused Ultrasound with Visualization and Calcium Hydroxylapatite for Improving Skin Laxity and Cellulite Appearance

Clinical evaluation of simultaneously applied monopolar radiofrequency and targeted pressure energy as a new method for noninvasive treatment of cellulite in postpubertal women

A validated photonumeric cellulite severity scale for the area above the knees: the knee cellulite severity score

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