Abstract:Conclusions: almost one-third of Cd patients needed surgical therapy in an early phase of their disease, and more than one-third of these underwent an emergency procedure. obstructive symptoms were the most common indication for surgery in the early phase of Cd.
“…Up to 75 per cent of patients, however, will require at least one surgical intervention. Surgical procedures comprise the majority of hospitalizations and 40 per cent of the economic cost, and relief of intestinal obstruction secondary to stricture formation represents more than half of all operations. Remission after surgery is short‐lived; 70 per cent of patients have endoscopic evidence of stricture recurrence within 1 year and 40 per cent will be symptomatic within 4 years, requiring reintervention.…”
Levels of circulating fibrocytes are raised in conditions marked by exaggerated fibrosis. These and other observations prompt a characterization of fibrocyte activity in CD with a view to investigating a pathogenic role.
“…Up to 75 per cent of patients, however, will require at least one surgical intervention. Surgical procedures comprise the majority of hospitalizations and 40 per cent of the economic cost, and relief of intestinal obstruction secondary to stricture formation represents more than half of all operations. Remission after surgery is short‐lived; 70 per cent of patients have endoscopic evidence of stricture recurrence within 1 year and 40 per cent will be symptomatic within 4 years, requiring reintervention.…”
Levels of circulating fibrocytes are raised in conditions marked by exaggerated fibrosis. These and other observations prompt a characterization of fibrocyte activity in CD with a view to investigating a pathogenic role.
“…Particularly in children, such intestinal complications are of great importance and may require urgent surgical management [8]. Intestinal obstruction represents an important percentage of causes required emergency surgery in patients with Inflammatory bowel disease [9,10].…”
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